Outcomes After Surgical Treatment of Pelvic Organ Prolapse

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Obstetrics and Gynecology".

Deadline for manuscript submissions: 15 December 2026 | Viewed by 4307

Special Issue Editors


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Guest Editor Assistant
Department of Obstetrics and Gynaecology, Lithuanian University of Health Sciences, LT-44307 Kaunas, Lithuania
Interests: pelvic organ prolapse; pelvic floor dysfunction; pelvic floor reconstructive surgery

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Guest Editor
Department of Urology, Surgery, and Obstetrics and Gynecology, Vanderbilt Medical Center, Nashville, TN, USA
Interests: female pelvic medicine; genitourinary reconstructive surgery; neurogenic bladder; pelvic floor reconstrucive surgery; urinary incontinence

Special Issue Information

Dear Colleagues,

Pelvic organ prolapse (POP) is a condition when one or several pelvic organs descend from their typical position. POP is more common among older patients than young. However, more and more young patients presently seek help for this pathology as it has a negative impact on quality of life. Genetics, sedentary lifestyle, obesity and other factors might play a role in this. Although the management of POP might be either conservative or surgical, operations look more attractive to young patients. Especially for those who want a fast result with the smallest efforts. This leads to a situation where operations for POP are performed earlier in life than it used to be.

According to various studies, the recurrence of prolapse after the surgical treatment of POP varies from 13% to 58%. This means that the earlier in life the operation is performed, the greater the risk is that the patient will be treated for the relapse of pelvic organ prolapse again later in life. Therefore, it is vital to choose not only between the conservative or surgical management of POP but also between various operations that have been developed to treat prolapse.

The aim of this Special Issue is to review the different methods of the surgical treatment of POP and the outcomes after applying them, with a particular focus on the recurrence of POP.

Dr. Justina Kačerauskienė
Guest Editor Assistant

Prof. Dr. Roger Roman Dmochowski
Guest Editor

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Keywords

  • pelvic organ prolapse
  • surgery
  • recurrence
  • vaginal hysterectomy
  • sacrocolpopexy
  • Manchester operation
  • sacrospinous fixation
  • native tissue 

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Published Papers (3 papers)

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Research

8 pages, 332 KB  
Article
Is Midline Uterosacral Plication Anterior Colporrhaphy Combo (MUSPACC) Procedure a Good Option in Management of Vaginal Vault Prolapse and Cystocele?
by Aiste Ugianskiene, Caroline Sollberger Juhl and Karin Glavind
Medicina 2026, 62(4), 709; https://doi.org/10.3390/medicina62040709 - 8 Apr 2026
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Abstract
Background and Objectives: After the publication by Haylen et al. introducing the MUSPACC (midline uterosacral plication anterior colporrhaphy combination) procedure, we implemented this technique in our clinical practice for the treatment of cystocele and vaginal vault prolapse (VVP). The aims of this [...] Read more.
Background and Objectives: After the publication by Haylen et al. introducing the MUSPACC (midline uterosacral plication anterior colporrhaphy combination) procedure, we implemented this technique in our clinical practice for the treatment of cystocele and vaginal vault prolapse (VVP). The aims of this study were to evaluate peri- and postoperative complications, as well as vaginal and urinary symptoms, including patient satisfaction 3 months postoperatively. Materials and Methods: A retrospective analysis was conducted on 58 women who underwent MUSPACC over a five-year period. Patient-reported outcomes were assessed using three prolapse-related items from the International Consultation on Incontinence–Vaginal Symptoms (ICIQ-VS) and the International Consultation on Incontinence Questionnaire–Urinary Incontinence Short Form (ICIQ-UI SF), administered preoperatively and at three months following surgery. Demographic characteristics, as well as perioperative and postoperative complications, were obtained through review of medical records. Results: At follow-up, patients demonstrated improvement in vaginal symptoms, with the mean preoperative ICIQ-VS score decreasing from 15.2 to 1.16. Among those with preoperative urinary incontinence (UI), 42.1% became completely dry after MUSPACC procedure alone. Three patients (15%) developed de novo UI. Perioperative complications occurred in one patient. The postoperative complication rate was 20.7% (12/58), including one patient who experienced a postoperative fistula between the right ureter and vagina. No further surgeries were required. Overall, 96.4% of patients were satisfied postoperatively. Conclusions: MUSPACC procedure appears to be an effective treatment for VVP and cystocele, with improvement in vaginal and urinary symptoms, high patient satisfaction, and a low rate of serious complications. Routine perioperative cystoscopy is now performed for immediate detection and management of urinary tract injuries. Full article
(This article belongs to the Special Issue Outcomes After Surgical Treatment of Pelvic Organ Prolapse)
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15 pages, 748 KB  
Article
Urinary Outcomes Following a Novel Reconstructive Pelvic Organ Prolapse Surgery: Randomized Controlled Trial
by Kristians Šušpanovs, Igors Ivanovs, Vilnis Lietuvietis, Ronalds Mačuks, Ieva Siksaliete, Dmitrijs Aleksandrovs and Dainis Krieviņš
Medicina 2026, 62(4), 619; https://doi.org/10.3390/medicina62040619 - 25 Mar 2026
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Abstract
Background and Objectives: The close anatomical relationship between pelvic support structures and the lower urinary tract contributes to high rates of urinary dysfunction among patients with pelvic organ prolapse (POP). POP reduction alone has been shown to alter urinary tract functioning. The aim [...] Read more.
Background and Objectives: The close anatomical relationship between pelvic support structures and the lower urinary tract contributes to high rates of urinary dysfunction among patients with pelvic organ prolapse (POP). POP reduction alone has been shown to alter urinary tract functioning. The aim of this study was to assess urinary functioning outcomes following a novel reconstructive surgical technique for POP. Materials and Methods: This randomized controlled trial was conducted between September 2024 and December 2025. The trial was registered in the German Clinical Trials Register (identifier: DRKS00038206), on 27 October 2025. Participants were randomly assigned to undergo either conventional laparoscopic sacrocervicopexy or the modified technique. Urinary outcomes were assessed using the International Consultation on Incontinence Questionnaire—Urinary Incontinence Short Form (ICIQ-UI), the Urogenital Distress Inventory Short Form (UDI-6), the cough test, and urodynamic testing. Assessments were performed prior to surgery and at a 6-month follow-up. Results: Both the classical and modified techniques resulted in significant improvements in ICIQ-UI and UDI-6 scores. However, no statistically significant differences were observed between groups. De novo SUI occurred in 14.3% of patients in the classical technique group and in no patients in the modified technique group. Conclusions: Urinary symptoms improved in both groups, with no statistically significant between-group differences. De novo SUI occurred only in the classical technique group, but this finding should be interpreted cautiously given the limited sample size. These results are exploratory and hypothesis-generating, and larger studies with longer follow-up are needed to clarify whether true between-group differences in postoperative continence outcomes exist. Full article
(This article belongs to the Special Issue Outcomes After Surgical Treatment of Pelvic Organ Prolapse)
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9 pages, 398 KB  
Article
The Manchester Procedure as a Uterine-Preserving Alternative for Uterine Prolapse Due to Cervical Elongation: A Short- and Mid-Term Clinical Analysis
by Claudia Liger Guerra, Lorena Sabonet Morente, Juan Manuel Hidalgo Fernandez, Manuel Navarro Romero, Cristina Espada Gonzalez and Jesus S. Jimenez-Lopez
Medicina 2025, 61(7), 1183; https://doi.org/10.3390/medicina61071183 - 29 Jun 2025
Viewed by 2965
Abstract
Background and Objectives: Pelvic organ prolapse (POP) is a prevalent condition that negatively impacts women’s quality of life. Uterine-preserving procedures are increasingly demanded by patients with uterine prolapse, particularly when associated with true cervical elongation. The Manchester procedure, historically used for uterine preservation, [...] Read more.
Background and Objectives: Pelvic organ prolapse (POP) is a prevalent condition that negatively impacts women’s quality of life. Uterine-preserving procedures are increasingly demanded by patients with uterine prolapse, particularly when associated with true cervical elongation. The Manchester procedure, historically used for uterine preservation, has regained interest due to its effectiveness and low morbidity. This study aims to evaluate the anatomical and functional outcomes of the Manchester procedure in women with uterine prolapse due to cervical elongation, assessing patient satisfaction and associated clinical factors. Materials and Methods: We conducted a retrospective, observational, single-center study at the Regional University Hospital of Málaga, Spain, including patients undergoing the Manchester procedure between January 2017 and December 2022. Inclusion criteria required a diagnosis of uterine prolapse due to clinically confirmed true cervical elongation. Surgical details, complications, and postoperative outcomes were recorded. Patient satisfaction was assessed using a Likert scale during follow-up visits. Results: A total of 38 patients were included, with a mean age of 48.7 years. All presented with symptomatic uterine prolapse and elongated cervix (>5 cm). The anatomical success rate was 97%, with only one case of symptomatic recurrence. The most common early postoperative complication was urinary tract infection (10.5%). The average follow-up duration was 18.6 months. A high level of satisfaction was recorded: 94.8% of patients were either “very satisfied” (73.7%) or “satisfied” (21.1%), and only 5.3% reported dissatisfaction. Multicompartmental repair (anterior and/or posterior colporrhaphy) improved satisfaction outcomes. Conclusions: The Manchester procedure is a safe, effective uterine-sparing surgical option for patients with cervical elongation-related uterine prolapse. It demonstrates a high anatomical success rate and low morbidity, with excellent patient satisfaction. Comprehensive preoperative assessment and addressing modifiable risk factors such as obesity and smoking are key to optimizing results. Further prospective studies are needed to assess long-term durability and quality-of-life outcomes. Full article
(This article belongs to the Special Issue Outcomes After Surgical Treatment of Pelvic Organ Prolapse)
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