Venous Thromboembolism Advances in Diagnosis and Treatment

Dear Colleagues,

Venous thromboembolism (VTE) represents the third leading cause of cardiovascular disease worldwide. The incidence of VTE has been rising in recent decades, likely due to increasing risk factors such as advancing age, obesity, and cancer. The role of inflammation in the so-called ‘immune-thrombosis’ is still the subject of several studies, also exploring the immune role of platelets and endothelial cells in the balance between immune response and thrombotic functions. The health burden of VTE requires identifying new biomarkers and molecular pathways involved in the pathogenesis of the disease in order to improve risk stratification and targeted prophylactic and therapeutic options. The optimal treatment choice and duration is also a matter of debate, in particular for specific clinical contexts such as vein thrombosis in atypical sites and frail patients with concomitant diseases. The current Special Issue focused on  advances in diagnosis and treatment of VTE welcomes submissions on the development and validation of diagnostic markers of VTE,  and its treatments with particular reference to ‘immune-thrombosis’, hematological malignancies, infections, and recurrences.

Prof. Mariasanta Napolitano
Guest Editor

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