Inorganic Polyphosphate Materials: Synthesis and Biomedical Applications
A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".
Deadline for manuscript submissions: 20 September 2026 | Viewed by 166
Editor
2. School of Life Sciences, Nanjing University, Nanjing 210093, China
3. Wuxi Xishan NJU Institute of Applied Biotechnology, Wuxi 214101, China
Interests: polyphosphate; synthetic biology; chemical biology; inorganic 2D materials; metalloprotein
Special Issue Information
Dear Colleagues,
Inorganic polyphosphate (polyP) is an ancient biomacromolecule widely present in various cell types. This polyanion and glassy polymer can coprecipitate with various multivalent cations to form amorphous solid materials, and can also form covalent bonds with other compounds through bioconjugations. Since Arthur Kornberg brought polyP back into the spotlight in the last century, its numerous biological functions have been unveiled. PolyP is a unique smart inorganic polymer integrating the dual functions of metabolic energy supply and morphogenetic signalling. Its adjustable linear polyanion chain can directly couple biological energy metabolism with regeneration processes, making it one-of-a-kind among biomaterials.
Although Jing Zhao, Henning J. Jessen, Bing Tian, and others have already made significant contributions regarding the synthesis and biological effects of polyP-based materials, from a materials perspective, gaps in the research of this biomaterial still remain. For example, research is lacking on the regulation of microstructures, novel synthesis strategies, broader biomedical applications, etc.
This Special Issue of Materials aims to highlight recent advances in polyP-based material research. Topics include, but are not limited to, novel synthetic strategies, new microstructures, and biomedical applications. Original research articles, methodological advances, and comprehensive reviews that expand our understanding of the structure and properties and their relationship with the functions of polyP-based materials are welcome.
Prof. Dr. Wei Wei
Guest Editor
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Keywords
- inorganic polyphosphate
- polyP
- polyP-based materials
- synthesis
- nano particles
- nano sheets
- microstructure
- biomedical applications
- biological functions
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