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Special Issue "Mechanism of Action Analysis for Marine Compounds"
A special issue of Marine Drugs (ISSN 1660-3397).
Deadline for manuscript submissions: closed (30 November 2013).
The marine environment provides a wealth of structurally and functionally interesting molecules. Whilst these molecules include many with exquisite biological activity, determination of definitive mechanisms of action is challenging.
Assays employed during isolation of marine natural products often determine activity against one of more individual targets or against cellular systems. These approaches do not guarantee that any identified target is the sole, or even primary, mediator of the biological activity and only rarely are compounds studied in sufficient depth to identify the full scope of potential targets.
From a pharmaceutical perspective, unidentified targets can lead to unexpected activities including side effects and complex structure activity relationships. This issue is devoted to studies which assess or apply bioactivity profiling through high content screens to provide an in-depth analysis of the mechanisms of action of marine natural products or their analogues.
Dr. Paul Teesdale-Spittle
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- mechanism of action
- high content screening
- bioactivity profiling
- chemical proteomics
- phenotypic analysis