Sustainable Production and Cultivation Systems for Coastal and Marine Organisms Targeting the Extraction of Bioactive Compounds

A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Marine Biotechnology Related to Drug Discovery or Production".

Deadline for manuscript submissions: 15 May 2024 | Viewed by 1445

Special Issue Editors


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Guest Editor
Centre of Marine Sciences—CCMAR, University of Algarve, 8005-139 Faro, Portugal
Interests: marine plants; biotechnological applications; antioxidant activity; antioxidants bioactivity; phytochemicals; natural product chemistry
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Centre of Marine Sciences—CCMAR, University of Algarve, 8005-139 Faro, Portugal
Interests: natural products; medicinal plants; halophytes; biological activities; bioactive molecules; biotechnological applications; saline cultivation; in vitro propagation
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Centre of Marine Sciences—CCMAR, University of Algarve, 8005-139 Faro, Portugal
Interests: marine biotechnology; halophyte plants; medicinal plants; natural products; marine biology; bioactive compounds
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The coastal and marine environment contains a vast scientific and economic potential, particularly concerning the organisms inhabiting it that are rich in bioactive metabolites and have numerous industrial applications. Yet such ecosystems are fragile and depend on a delicate balance, and their exploitation via wild harvesting has clear negative impacts. Therefore, sustainable systems that allow for the production and cultivation of such resources are crucial for their adequate exploitation while preserving these natural habitats. This Special Issue will provide researchers with a platform to publish studies regarding the use/optimization of different production systems applied to target organisms or specific marine bioactive natural compounds, including small, medium, and large bioproduction processes, as well as biorefinery approaches and cultivation techniques. Target organisms include marine organisms (i.e., algae, seagrasses, and marine animals), and coastal plants (i.e., species living in close connection with/distance to the marine environment). Submissions of all the article types accepted by Marine Drugs are welcome.

Dr. Luísa Custódio
Dr. Maria João Rodrigues
Dr. Catarina Guerreiro Pereira
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bioactive compounds
  • sustainable production
  • sustainable cultivation
  • coastal organisms
  • marine organisms
  • biological activities

Published Papers (1 paper)

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Research

14 pages, 2704 KiB  
Article
Enhanced Photosynthetic Pigment Production Using a Scaled-Up Continuously Circulated Bioreactor
by Won-Kyu Lee, Yong-Kyun Ryu, Taeho Kim, Areumi Park, Yeon-Ji Lee, In Yung Sunwoo, Eun-Jeong Koh, Chulhong Oh, Woon-Yong Choi and Do-Hyung Kang
Mar. Drugs 2023, 21(11), 576; https://doi.org/10.3390/md21110576 - 02 Nov 2023
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Abstract
Microalgae have gained attention as a promising source of chlorophylls and carotenoids in various industries. However, scaling up of conventional bubble columns presents challenges related to cell sedimentation and the presence of non-photosynthetic cells due to non-circulating zones and decreased light accessibility, respectively. [...] Read more.
Microalgae have gained attention as a promising source of chlorophylls and carotenoids in various industries. However, scaling up of conventional bubble columns presents challenges related to cell sedimentation and the presence of non-photosynthetic cells due to non-circulating zones and decreased light accessibility, respectively. Therefore, this study aimed to evaluate the newly developed continuously circulated bioreactor ROSEMAX at both laboratory and pilot scales, compared to a conventional bubble column. There was no significant difference in the biomass production and photosynthetic pigment content of Tetraselmis sp. cultivated at the laboratory scale (p > 0.05). However, at the pilot scale, the biomass cultured in ROSEMAX showed significantly high biomass (1.69 ± 0.11 g/L, dry weight, DW), chlorophyll-a (14.60 ± 0.76 mg/g, DW), and total carotene (5.64 ± 0.81 mg/g, DW) concentrations compared to the conventional bubble column (1.17 ± 0.11 g/L, DW, 10.67 ± 0.72 mg/g, DW, 3.21 ± 0.56 mg/g, DW, respectively) (p ≤ 0.05). Flow cytometric analyses confirmed that the proportion of Tetraselmis sp. live cells in the culture medium of ROSEMAX was 32.90% higher than that in the conventional bubble column, with a photosynthetic efficiency 1.14 times higher. These results support suggestions to use ROSEMAX as a bioreactor for industrial-scale applications. Full article
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