Marine Natural Products as Promising Modulators of Ferroptosis
A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Marine Pharmacology".
Deadline for manuscript submissions: 15 June 2026 | Viewed by 3
Special Issue Editor
Interests: marine fungi; metabolites; antitumor; anti-ferroptotic; antibacterial
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Ferroptosis is an iron-dependent, lipid peroxidation-driven form of cell death implicated in neurodegenerative diseases, ischemic injury, and tumor progression. Although its modulation holds therapeutic promise, current synthetic inhibitors, such as ferrostatin-1, suffer from poor metabolic stability and bioavailability, underscoring the need for novel chemotypes. Natural products, with their distinct structural diversity and biocompatibility, offer a promising source for new ferroptosis modulators. In particular, the marine environment provides a rich and largely unexplored reservoir of architecturally unique metabolites. These marine-derived compounds represent ideal starting points for developing targeted therapeutics capable of inducing or inhibiting ferroptosis in specific disease contexts.
In this Special Issue, research papers and reviews should focus on topics such as the characterization, chemical synthesis, structural modification, biosynthesis, pharmaceutical mechanisms, or the therapeutic potential of ferroptosis modulators.
Dr. Zhongbin Cheng
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- marine natural products
- ferroptosis modulators
- inhibitors
- inducer
- isolation and structural identification
- activity
- mechanism
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