Orthopedic Tumor Surgery as Part of a Multimodal Therapy Concept – Enhancing Outcomes and Survivals
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: closed (15 August 2022) | Viewed by 518
Special Issue Editors
Interests: pelvic and acetabular surgery; tumor surgery; tumor endoprostheses; reconstructive surgery; polytrauma management
Special Issues, Collections and Topics in MDPI journals
Interests: soft tissue sarcoma; urooncology; translational research
Special Issue Information
Dear Colleagues,
Ongoing developments in tumor therapies lead to a better understanding of tumor biology and the improved survival of patients. However, secondary to this fact, the number of patients with bone metastases continues to increase. Additionally, the incidence of primary bone tumors has also continued to grow in recent decades.
Treating these lesions needs a wide armamentarium of surgical skills regarding resection and reconstruction techniques. These lesions can impair the extremities, i.e., impending or pathologic fractures, and central structures when located at the spine or the pelvis. Commonly, these lesions lead to painful restrictions of patients' mobility, reduced quality of life, and, most significantly, their daily independence. However, skeletal lesions are not the only focus of the treatment team; more and more cases appear where the combined resections of skeletal and lung or visceral metastases are sometimes required.
The surgical treatment of malignant bone lesions is often a major surgery, frequently performed on patients with multiple comorbidities and a high risk of mortality. Therefore, the current view is that the surgical strategy should be embedded in a multidisciplinary approach. This aims to optimize the general oncologic outcome, minimize surgical trauma, reduce postoperative morbidity, and improve the postoperative quality of life.
This Special Issue intends to highlight all aspects of an interdisciplinary approach in orthopedic tumor surgery performed in different types of cancer patients, emphasizing sarcomas. Potential topics of interest, among others, for this Special Issue are interdisciplinary decision making, surgical techniques and the selection of implants, patient survival, prediction of survival, surgical complications, functional results, quality of life, multimodal therapy concepts, adjuvant therapy regimes, and health economics.
Dr. Sven Märdian
Prof. Dr. Anne Flörcken
Guest Editors
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Keywords
- bone metastases
- pathologic fracture
- impending fracture
- adjuvant radiotherapy
- adjuvant chemotherapy
- primary bone tumor
- secondary bone tumor
- resection techniques for metastases
- survival metastases
- reconstruction of pathologic bone leasons
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