Glial Cell Physiology and Central Nervous System Injury

Dear Colleagues,

Glial cells play an active role in physiology and cerebrovascular disease; they maintain the cytoarchitecture and regulate extracellular environment homeostasis in the central nervous system. As, without them, neurons do not play their normal function in healthy tissue, they are also principal responders to central nervous system injury. The responses of glial cell to injury can potentially affect neuronal cell interaction and central nervous system function. After the onset of cerebrovascular disease, glial cells undergo numerous pathological alterations over time, including morphological change and rapid proliferation; therefore, understanding the spatial and temporal changes of glial cells at molecular and cellular levels will provide therapeutic strategy insight. This issue aims to identify genetic factors and intercellular cross talk of glial cells to contribute to cerebrovascular injury.

Dr. Zhijun Zhang
Guest Editor

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• glial cells
• central nervous system injury
• genetic factor
• intercellular cross talk
• extracellular environment homeostasis