Frontier Research of Adhesion GPCRs in the Function of the Brain
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".
Deadline for manuscript submissions: closed (26 August 2022) | Viewed by 243
Special Issue Editor
Special Issue Information
Dear Colleagues,
Adhesion G protein-coupled receptors (aGPCRs) consist of thirty-three members as a sub-class of the GPCR family in humans. Human-disease-related mutations have been discovered in several aGPCRs. For example, loss-of-function mutations in GPR56 cause bilateral frontoparietal polymicrogyria (BFPP). Further studies have uncovered a part of aGPCRs’ roles in angiogenesis, neurodevelopment, synaptic pruning, myelination, and cancer progression. However, the functions of most aGPCRs are still unknown, especially in the central neural system.
In this Special Issue, we will collect advances and reviews focusing on the current discoveries and opinions about the functions of aGPCRs related to brain health and disease.
Dr. Tao Li
Guest Editor
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Keywords
- adhesion GPCRs
- central neural system
- neurodegenerative diseases
- brain development
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