Clinical and Radiological Perspectives in Rhinosinusal Pathology

Dear Colleagues,

Sinus pathology constitutes the predominant category of clinical presentations in otorhinolaryngology departments, representing a significant proportion of both acute and chronic cases. Patients frequently present with a constellation of symptoms that may be specific or nonspecific in nature. These include nasal obstruction, rhinorrhea, facial pressure or fullness, hyposmia, and, in many cases, pain localized to the projection areas of the paranasal sinuses.

The diagnostic process relies primarily on clinical assessment, but it is substantially strengthened through imaging investigations. In this regard, computed tomography (CT) and cone-beam computed tomography (CBCT) play a crucial role in determining the extent of disease, identifying anatomical variants, and informing therapeutic decision-making.

The overarching aim of this Special Issue is to provide an in-depth exploration of the diverse etiologies of rhinosinusitis, encompassing viral, bacterial, and fungal origins. Beyond the microbial spectrum, particular emphasis will be placed on the contribution of predisposing anatomical and physiological factors, such as abnormal pneumatization of the paranasal cavities. Moreover, the intricate interplay between rhinosinusal pathology and systemic or comorbid conditions, such as headache, migraine, and depression, will be examined to highlight the broader clinical impact of these disorders. Special attention will be given to studies that integrate clinical expertise with advanced imaging techniques, thereby offering a multidimensional perspective on diagnosis and management.

This Special Issue welcomes the submission of original research articles, narrative and systematic reviews, as well as meta-analyses, with the shared objective of advancing the understanding, diagnosis, and therapeutic strategies related to rhinosinusal pathology. Contributions addressing innovative treatment modalities, surgical techniques, and evidence-based management protocols are particularly encouraged, as they hold promise for improving patient outcomes and shaping future clinical practice.

Dr. Alin Horatiu Nedelcu
Dr. Ancuta Lupu
Dr. Vasile Valeriu Lupu
Guest Editors

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