Musculoskeletal Disorders: Integrative Insights into Pathophysiology, Therapeutic Strategies, and Rehabilitation
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: 30 May 2026 | Viewed by 47
Special Issue Editor
Interests: ultrasound Imaging; rehabilitation; connective tissue; regenerative medicine; sports injuries; biomechanics; neurorehabilitation; musculoskeletal disorders
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Musculoskeletal disorders (MSDs) remain among the leading causes of pain, disability, and loss of productivity worldwide, profoundly affecting individuals across their lifespan. This Special Issue aims to provide a comprehensive and interdisciplinary exploration of the current understanding and future directions in the pathophysiology, clinical management, and rehabilitation of musculoskeletal conditions. Advancements in molecular biology, neuroimmunology, and tissue biomechanics have shed new light on the complex mechanisms underlying MSDs, ranging from inflammation-driven degeneration to mechanotransductive imbalances within connective and neuromuscular tissues. A central objective of this issue is to bridge the gap between basic science and clinical application, emphasizing how novel diagnostics, including high-resolution imaging and biomarker analysis, can inform more targeted therapeutic strategies. We invite contributions focusing on innovative pharmacological and non-pharmacological interventions, including regenerative approaches (e.g., stem cell therapies, platelet-rich plasma, and extracellular vesicles), integrative rehabilitation programs, and emerging technologies such as AI-assisted diagnostics, wearable sensors, and ultrasound-guided therapies. Particular attention will be given to patient-centered, functionally oriented outcomes and the role of personalized rehabilitation pathways in restoring mobility and quality of life. This issue seeks to foster cross-disciplinary dialogue among physiatrists, orthopedists, neuroscientists, bioengineers, and rehabilitation specialists. By integrating diverse perspectives, we aim to redefine the landscape of musculoskeletal medicine and contribute to the development of more effective, individualized, and evidence-based care models.
Dr. Carmelo Pirri
Guest Editor
Manuscript Submission Information
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Keywords
- musculoskeletal disorders
- high-resolution imaging
- biomarkers
- ultrasound-guided therapy
- regenerative medicine
- personalized rehabilitation
- wearable sensors
- translational musculoskeletal research
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