Clinical Applications of Functional MRI Techniques and 3D Images
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Radiobiology and Nuclear Medicine".
Deadline for manuscript submissions: 31 January 2027 | Viewed by 262
Special Issue Editor
Interests: quantitative MRI; head and neck cancer; three-dimensional CT; dentomaxillofacial radiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Functional/quantitative MRI offer unique capabilities to probe biological mechanisms at the level of the tissue microenvironment. By enabling quantitative measurements, these approaches can generate objective imaging biomarkers for clinical management. Among these techniques, diffusion-weighted imaging (DWI) has become one of the most established and widely implemented functional MRI methods and is routinely incorporated into numerous clinical MRI protocols. Further ongoing technical advances in diffusion imaging continue to expand its diagnostic and prognostic potential.
The evolution of functional MRI extends far beyond diffusion imaging. A range of other techniques, such as chemical exchange saturation transfer (CEST) imaging, dynamic contrast-enhanced (DCE) imaging, MR spectroscopy, T1ρ imaging, and macromolecular proton fraction (MPF) imaging, have been explored in both preclinical and clinical contexts. These methods offer complementary insights into tissue composition, metabolism, perfusion, and molecular processes, and have shown encouraging results for applications in disease detection, characterization, and treatment monitoring.
In parallel, the integration of advanced computational post-processing with three-dimensional (3D) imaging has greatly expanded the scope of 3D imaging in clinical practice. High-resolution volumetric datasets, combined with sophisticated image analysis algorithms, provide powerful tools for visualizing anatomy, quantifying pathology, and planning interventions. Three-dimensional imaging therefore holds the potential to transform patient management by enabling more precise and personalized approaches.
This Special Issue aims to bring together original research, technical developments, and comprehensive reviews that explore the clinical applications and potential value of functional MRI and 3D imaging. We invite contributions that highlight novel methodologies, validation studies, and evidence-based use cases that bridge the gap between advanced imaging science and everyday clinical practice.
Dr. Qiyong Hemis Ai
Guest Editor
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Keywords
- functional MRI
- quantitative MRI
- 3D imaging
- clinical application
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