Special Issue "Metabolic Biochemistry During Exercise: Contemporary Understandings and New Approaches to Improved Models, Methodologies and Data Interpretations"

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Biochemistry, Biophysics and Computational Biology".

Deadline for manuscript submissions: 30 November 2023 | Viewed by 97

Special Issue Editor

Dr. Robert Andrew Robergs
E-Mail Website
Guest Editor
School of Exercise and Nutrition Sciences, Faculty of Health, Queensland University of Technology, Kelvin Grove, Queensland, Australia
Interests: systems physiology during exercise; muscle metabolism, biochemistry of metabolic acidosis; indirect calorimetry during exercise; VO2 kinetics to steady state in addition to incremental and non-steady state exercise

Special Issue Information

Dear Colleagues,

This Special Issue is centered around the need to challenge convention in the understanding of the biochemistry of the energetics of skeletal muscle contraction during exercise, in addition to the systemic acidosis responses to numerous disease processes. The underlying model of most prior studies of muscle metabolism has been based on whole-body (wb) gas exchange, limb gas exchange, and whole muscle samples (human muscle biopsy, human magnetic resonance imaging and spectroscopy, animal limb models and biopsy, etc.), with limited recognition of the limitations imposed by these methods due to the All Or None Law of muscle contraction combined with the Size Principle of motor unit recruitment.

Core topics that challenge the conventions of important wb oxygen consumption (wb-VO2) measures (maximal VO2 (VO2max); VO2 gain; VO2 kinetics; and the economy and efficiency of muscle contractions during exercise), the biochemistry of skeletal muscle metabolic acidosis, and skeletal-muscle-fiber-type-specific biochemistry of energy metabolism will be presented with the overarching purpose of (1) stimulating the further understanding, interest, and research into these topics, and (2) improving the understanding of how the realities of the All Or None Law of muscle contraction combined with the Size Principle of motor unit recruitment influence skeletal muscle metabolism.

Dr. Robert Andrew Robergs
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • skeletal muscle
  • energy catabolism
  • oxygen consumption (VO2)
  • acidosis
  • VO2 kinetics
  • efficiency
  • economy
  • glycolysis
  • lactate
  • glycogen
  • fatigue
  • disease

Published Papers

This special issue is now open for submission.
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