Understanding Early Dysmetabolism in Adolescents: Bridging Research, Mechanisms and Clinical Management

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: 31 May 2026 | Viewed by 11

Special Issue Editor


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Guest Editor
Department of Woman, Child, and General and Specialized Surgery, University of Campania “Luigi Vanvitelli”, Naples, Italy
Interests: pediatric obesity; pediatric MASLD; obesity comorbidities; pediatric endocrinology; pediatric nephrology; general pediatrics

Special Issue Information

Dear Colleagues,

The rising prevalence of metabolic disorders—such as insulin resistance (IR), obesity, and type 2 diabetes (T2D)—in children and adolescents has become a critical global health challenge, underscoring the urgent need for early identification and intervention.

This Special Issue invites contributions that explore the underlying mechanisms of dysmetabolism in adolescents and highlight the potential for early biomarkers to inform both research and clinical practice. We aim to synthesize cutting-edge research investigating the biological pathways that contribute to metabolic disturbances in pediatric populations, taking into consideration genetic, environmental, and lifestyle factors.

We particularly encourage submissions that focus on early markers of dysmetabolism, from molecular indicators like IR to broader metabolic profiles. Studies integrating mechanistic insights with clinical management strategies are especially welcome.

Given the ongoing challenges in diagnosing and managing these conditions in children and adolescents, we also invite papers that explore innovative approaches to early detection and intervention, including lifestyle modifications and pharmacological treatments.

By bridging scientific research with clinical practice, this Special Issue seeks to establish a comprehensive framework for the development of advanced diagnostic methodologies and more effective management strategies in pediatric healthcare, with the ultimate goal of driving significant progress in addressing the growing public health challenge of pediatric dysmetabolism.

Dr. Anna Di Sessa
Guest Editor

Manuscript Submission Information

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Keywords

  • dysmetabolism
  • biomarkers
  • intervention
  • prevention
  • early diagnosis
  • strategies
  • children
  • adolescents

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Published Papers

This special issue is now open for submission.
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