Lipid Metabolism and Cellular Stress Pathways in Cancer, Normal Tissue Injury and Therapeutic Response
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".
Deadline for manuscript submissions: 16 February 2027 | Viewed by 37
Editor
2. Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA
Interests: lipid metabolism; cellular stress responses; oxidative stress; radiation-induced normal tissue toxicity; chemotherapy-induced nephrotoxicity; cancer biology; tumor microenvironment; DNA damage response; inflammation; salivary gland toxicity; kidney injury; radiobiology; nanomedicine; biomarkers of tissue injury; therapeutic strategies to reduce cancer treatment-related toxicities
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Lipid metabolism and cellular stress pathways are increasingly recognized as key regulators of cancer progression, therapeutic response, tissue injury and organ dysfunction. Alterations in lipid signaling, membrane homeostasis, oxidative stress, mitochondrial function, inflammatory responses, DNA damage repair and cell death pathways contribute not only to tumor growth and treatment resistance but also to normal tissue toxicities caused by radiation therapy, chemotherapy, targeted agents, immunotherapy and radioligand therapy. Understanding these interconnected mechanisms is essential for developing safer and more effective therapeutic strategies. This Special Issue aims to highlight recent advances in the molecular, cellular and translational biology of lipid dysregulation and stress–response pathways in cancer and treatment-induced normal tissue injury. The topic is well aligned with the scope of Life, as it integrates fundamental mechanisms of cell biology, disease pathogenesis, therapeutic response and translational biomedical research. We particularly encourage studies that identify novel biomarkers, mechanistic pathways and protective interventions that reduce normal tissue damage while preserving or improving anticancer efficacy. In this Special Issue, original research articles, reviews, short communications and translational studies are welcome. Research areas may include, but are not limited to, lipid metabolism, oxidative and ER stress, mitochondrial dysfunction, inflammation, fibrosis, DNA damage response, radiobiology, chemotherapy-induced organ injury, cancer therapy resistance, tumor–normal tissue interactions, nanomedicine, biomarkers and therapeutic strategies targeting cellular stress pathways. We look forward to receiving your valuable contributions.
Dr. Anis Ahmad
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- lipid metabolism
- cellular stress
- oxidative stress
- normal tissue toxicity
- cancer therapy
- radiobiology
- chemotherapy-induced injury
- DNA damage response
- inflammation
- biomarkers
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