Recent Advances in Head and Neck Disorders

Dear Colleagues,

Otolaryngology and head and neck surgery (OHNS) represent rapidly evolving specialties in which technological and scientific progress is continuing to redefine standards of care. Breakthroughs in areas such as molecular biology, advanced imaging, reconstructive innovations, and intraoperative guidance systems are transforming how clinicians diagnose and treat complex conditions. Current research is demonstrating tangible benefits in terms of diagnostic accuracy, surgical precision, and therapeutic diversity, with significant strides being made in oncology, otology, skull base surgery, and head and neck reconstruction.

Importantly, the focus of OHNS has shifted beyond survival metrics alone. Quality of life and functional preservation are now integral endpoints in modern treatment strategies. Particularly in oncological contexts, contemporary protocols emphasize not only prolonging life expectancy but also safeguarding well-being, functional outcomes, and social reintegration. Advances in reconstructive surgery, rehabilitation, and survivorship care models exemplify this patient-centered approach.

At the same time, the development of non-invasive diagnostic technologies—including liquid biopsies, hyperspectral imaging, diffusion-weighted MRI, and fluorescence-guided surgery—shows potential in achieving earlier disease detection and reduced treatment burden. With the integration of artificial intelligence and computational models, these tools can further refine prediction models, personalize treatment pathways, and minimize unnecessary interventions. These innovations hold the potential to deliver the highest benefits of modern science directly to patients, ensuring not only prolonged survival but also sustained functional well-being and satisfaction with quality of life.

Hence, we encourage researchers to contribute original studies and comprehensive reviews that highlight innovations in diagnostic technologies, emerging therapeutic approaches, and the intricate connections between oral diseases and overall health, particularly through the lens of cellular, molecular, and systems-level biology.

Dr. Cosmin Ioan Faur
Dr. Maximilian Dindelegan
Guest Editors

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