Epidemiological Insights into Cardiovascular Risk and Outcomes

Dear Colleagues,

Despite major advances in prevention, diagnosis, and treatment, cardiovascular disease remains the leading cause of morbidity and mortality worldwide. Epidemiological studies continue to be crucial to understanding the complex interplay of genetic, behavioral, environmental, and social determinants that shape cardiovascular risk across populations. Recent advances in large-scale cohort studies, biobanks, and digital health technologies have expanded our ability to quantify risk, uncover novel biomarkers, and track outcomes across diverse demographic and geographic contexts.

This Special Issue aims to bring together cutting-edge research that deepens our understanding of cardiovascular risk and outcomes from an epidemiological perspective. We welcome not only investigations into risk factors and primary prevention, but also epidemiological studies focused on major cardiovascular outcomes such as heart failure, atrial fibrillation, stroke, and myocardial infarction. Longitudinal patterns in disease progression, the impact of social determinants and health inequities, and the role of new analytical approaches—including machine learning and systems epidemiology—in predicting and preventing CVD are of interest to this number. Studies leveraging population-based data, electronic health records, registries, mendelian randomization, or other innovative study designs to inform clinical and public health strategies are also encouraged.

Prof. Dr. Rui Providência
Guest Editor

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