The Impact of Onconutraceutics as Potential Oncological Strategy
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".
Deadline for manuscript submissions: 24 April 2026 | Viewed by 17
Special Issue Editors
Interests: biochemical pathways in cancer cell death (apoptosis, necrosis, necroptosis, autophagy and anoikis); nutrition and human diseases; oxidative stress; signal transduction; targeted therapies; cancer stem-like cells; analysis of the behaviours of phytocompounds in obesity treatment
Special Issues, Collections and Topics in MDPI journals
Interests: ROS-natural compounds in cancer therapy; apoptosis induction and cell cycle arrest by plant-derived molecules; ROS-mediated cytotoxicity and redox balance in tumor and non-tumor cells; antioxidant defense systems; cell death and survival pathways in cancer (apoptosis, necrosis, autophagy)
Special Issue Information
Dear Colleagues,
Nutraceuticals are bioactive compounds that show a growing scientific interest for their potential therapeutic properties. In particular, their use in the prevention and treatment of complex diseases such as cancer has been the subject of numerous studies. Current oncological therapies, including chemotherapy, radiotherapy, and surgery, while representing well-established and effective approaches, are often associated with significant side effects that compromise the quality of life and the overall health of patients. In this scenario, onconutraceuticals emerge as a possible complementary strategy, capable of targeting specific molecular pathways that regulate cell proliferation, apoptosis, angiogenesis, and the inflammatory response, which are key processes in tumors. Therefore, it is crucial to understand the molecular mechanisms underlying the action of onconutraceuticals and to carefully evaluate their possible synergistic or antagonistic interactions with conventional anticancer drugs. This Special issue provides an updated overview of the main molecular pathways modulated by onconutraceuticals, highlighting their potential role as support in oncological therapeutic strategies and underscoring the need for further preclinical and clinical studies to define their efficacy and safety. We invite you to contribute with original papers or review articles to this Special Issue, which will deepen our knowledge of new drug candidates and their mechanisms of action.
Prof. Dr. Antonella D'Anneo
Dr. Federica Affranchi
Guest Editors
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Keywords
- nutraceuticals
- oncological therapies
- onconutraceuticals
- molecular pathways modulated by onconutraceuticals
- chemotherapy
- radiotherapy
- personalized therapies
- non-invasive approaches
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