A Personalized, Contemporary Approach to Cardiovascular Medicine: Novel Insights and Mechanisms

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Mechanisms of Diseases".

Deadline for manuscript submissions: closed (30 September 2020) | Viewed by 1672

Special Issue Editor


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Guest Editor
1. Ciccarone Center for the Prevention of Heart Disease, Department of Cardiology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
2. Advent Health Medical Group, Orlando, FL, USA
Interests: cardiovascular disease; prevention; coronary artery disease; coronary artery calcium; risk assessment; lipids; cholesterol

Special Issue Information

Dear Colleagues,

Despite many advances in diagnosis and treatment, cardiac disease still accounts for the highest percentage of deaths worldwide. The last decade has seen a rise in the personalized risk stratification of persons at risk of heart disease, novel genetic determinants of certain cardiac disorders including hypertrophic cardiomyopathy, dilated cardiomyopathies and hyperlipidemia, as well as newer immune-mediated cholesterol therapies. This Special Issue of the Journal of Personalized Medicine aims to review the most significant discoveries in the diagnosis and treatment of cardiac disease, with a clear focus on the increasing personalization of the approach to cardiac care. Our goal is to attract the most significant new cardiac research regarding personalized medicine, as well as to review the game-changing personalization of cardiac care in the last decade. We are soliciting original research articles and review articles for this Special Issue.

Dr. Rajesh Tota-Maharaj
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cardiac
  • prevention
  • personalized cardiac care
  • lipids
  • genetics

Published Papers (1 paper)

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3 pages, 172 KiB  
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Reply to Comment: Evaluation of the Association of Omentin 1 rs2274907 A > T and rs2274908 G > A Gene Polymorphisms with Coronary Artery Disease in Indian Population: A Case–Control Study
by Chandan K. Jha, Rashid Mir, Imadeldin Elfaki, Jamsheed Javid, Abdullatif Taha Babakr, Shaheena Banu and S. M. S. Chahal
J. Pers. Med. 2020, 10(4), 194; https://doi.org/10.3390/jpm10040194 - 26 Oct 2020
Viewed by 1424
Abstract
Coronary artery disease (CAD) is a major cause of death all over the world. CAD is caused by atherosclerosis which is induced by the interaction of genetic factors and environmental factors. Genome-wide association studies have revealed the association of certain gene polymorphisms with [...] Read more.
Coronary artery disease (CAD) is a major cause of death all over the world. CAD is caused by atherosclerosis which is induced by the interaction of genetic factors and environmental factors. Genome-wide association studies have revealed the association of certain gene polymorphisms with susceptibility to CAD. Omentin 1 is an adipokine secreted by the visceral adipose tissues and has been reported to have anti-inflammatory, cardioprotective, and enhances insulin sensitivity. In this study, we examined the role of omentin-1 common single nucleotide polymorphisms (SNPs) (rs2274907 A > T and rs2274908 G > A) in CAD. We conclude that the AT genotype and the T allele of the rs2274907 A > T is associated with Cad in the south Indian population. Our results indicated that the rs2274907 SNP may be associated with CAD in this population. This finding needs further validation in well-designed and large-sample size studies before being introduced in clinical settings. Full article
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