Chemotherapy and Hematopoietic Stem Cell Transplantation

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Regenerative Medicine and Therapeutics".

Deadline for manuscript submissions: 15 November 2025 | Viewed by 77

Special Issue Editor


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Guest Editor
Pediatric Hematology-Oncology Department, La Paz University Hospital, 28046 Madrid, Spain
Interests: transfusion medicine; pediatrics; hematology; hematopoyetic stem cell transplantation; graft versus host disease

Special Issue Information

Dear Colleagues,

Chemotherapy and hematopoietic transplantation have revolutionized the treatment of hematologic malignancies and other life-threatening disorders, offering curative potential for many patients. The advent of personalized medicine has further transformed this field by tailoring treatments to the genetic, molecular, and immunologic profiles of individual patients, thereby optimizing efficacy while minimizing toxicity.

Since the first successful bone marrow transplants in the mid-20th century, advances in conditioning regimens, donor selection, and supportive care have significantly improved patient outcomes. Recent progress in genomic and immunological profiling has allowed for the refinement of both chemotherapy and transplantation protocols, moving toward a more patient-specific approach.

This Special Issue aims to explore recent innovations in chemotherapy and hematopoietic transplantation, with a particular emphasis on how personalized medicine is shaping these fields. Topics will include novel agents, conditioning strategies, and emerging cellular therapies, all within the context of tailoring treatments to individual patient characteristics.

We welcome studies that highlight personalized approaches to reduced-toxicity conditioning, targeted therapies, graft-versus-host disease prevention, and the integration of gene editing and immunotherapy into transplantation. Particular interest will be given to research that demonstrates how molecular and genomic insights are being translated into clinical practice.

We encourage submissions of original research, reviews, and other types that contribute to a deeper understanding of chemotherapy and transplantation in the era of personalized medicine. Papers that explore translational and clinical advancements in tailoring treatments to individual patient profiles will be highly valued.

Dr. Luisa Sisinni
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hematopoietic stem cell transplantation
  • chemotherapy toxicity and conditioning regimens
  • graft-versus-host disease (GVHD) management
  • immunotherapy and cellular therapies

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Published Papers

This special issue is now open for submission.
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