Prevention and Treatment of Cryptococcal Meningitis
A special issue of Journal of Fungi (ISSN 2309-608X). This special issue belongs to the section "Fungal Pathogenesis and Disease Control".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 703
Special Issue Editor
Special Issue Information
Dear Colleagues,
The global burden of cryptococcal meningitis (CM) remains unacceptably high. HIV-associated CM claims over 100,000 lives every year and accounts for around 20% of all HIV-related deaths. Furthermore, cases are not decreasing in most African countries due to continued late presentation of patients with HIV infection, and patients falling out of care and interrupting antiretroviral therapy. Furthermore, non-HIV CM cases are now the majority in many developed country settings, and there are few recent studies to guide best practice in this heterogeneous group, for whom treatment is often very challenging.
For this issue, we invite reviews and research articles that add to and review the evidence base for current guidelines and practice and ongoing implementation efforts; studies to optimise the cryptococcal antigen screen and presumptive treatment strategy to prevent HIV-associated CM; and promising new evidence and avenues that could help reduce the global burden of both HIV-associated and non-HIV-associated cryptococcal infection.
Dr. Thomas S. Harrison
Guest Editor
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Keywords
- cryptococcal meningitis
- cryptococcal antigen
- screening antifungals
- amphotericin
- fluconazole
- flucytosine
- liposomal amphotericin
- HIV-associated
- non-HIV-associated intracranial pressure
- immune reconstitution
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