Diversity and Secondary Metabolites of Endophytic Fungi

Dear Colleagues,

This Special Issue will be dedicated to the diversity and secondary metabolites of endophytic fungi. Endophytic fungi are highly diverse microorganisms that inhabit the host plant tissues intracellularly or/and intercellularly. There are approximately one million endophytic fungi in the world. Their wide distribution and co-existence with their host plants in nature indicates their life power and excellent living strategy for dealing with their hosts and their competitors. Endophytic fungi offer significant advantages to the host plants by producing various metabolites to counter the attack from pathogens, insects, and herbivores. They are a promising group of microorganisms that produce plant-associated bio-active metabolites with diverse chemical entities and structural functions. Metabolites isolated from endophytic fungi exhibited various pharmacological properties. In the past few decades, many novel bio-active natural products from endophytic fungi have been discovered that have anticancer, antiviral, antibacterial, and antifungal activities. These fungi produce a wide range of secondary metabolites belonging to the alkaloids, macrolides, terpenoids, and peptide derivatives, as well as other structure classes. However, it is estimated that more than 92% of endophytic fungi are still unknown, this situation largely limits the development and utilization of such important microorganisms. Therefore, a study on the diversity and secondary metabolites of endophytic fungi is of great significance. In this topic, we would like to discover more novel species of endophytic fungi via focusing on their diversity and secondary metabolites.

Prof. Dr. Ji-Chuan Kang
Prof. Dr. Yongzhong Lu
Guest Editors

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