Medical Implants for Biomedical Applications

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Biomaterials and Devices for Healthcare Applications".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 551

Special Issue Editors


E-Mail Website
Guest Editor
Division of Oral Surgery and Implantology, Department of Head and Neck and Sensory Organs, Fondazione Policlinico Universitario A. Gemelli IRCCS—Università Cattolica del Sacro Cuore, 00168 Rome, Italy
Interests: implant prosthodontics; prosthodontics
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Division of Oral Surgery and Implantology, Department of Head and Neck and Sensory Organs, Fondazione Policlinico Universitario A. Gemelli IRCCS—Università Cattolica del Sacro Cuore, 00168 Rome, Italy
Interests: implant prosthodontics; prosthodontics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The field of medical implants stands at the forefront of innovation in healthcare, offering life-changing solutions for millions of patients worldwide. With rapid advancements in technology and a growing understanding of human biology, medical implants are becoming increasingly sophisticated, addressing a wide range of medical challenges, from restoring mobility to repairing critical organs and tissues.

This upcoming Special Issue, Medical Implants for Biomedical Applications, will serve as a dedicated platform with which to explore cutting-edge developments in this dynamic field. It aims to showcase pioneering research, innovative designs, and emerging technologies that are shaping the future of medical implants. Contributions will span topics such as advanced biomaterials, next-generation manufacturing techniques, biocompatibility, and smart implant systems that integrate sensors or therapeutic delivery mechanisms.

We invite submissions that address key challenges, such as implant durability, immune response mitigation, infection prevention, and personalized medicine applications. Our goal is to highlight interdisciplinary approaches that bridge engineering, biology, and clinical practice, fostering new collaborations to push the boundaries of what medical implants can achieve.

By bringing together a diverse array of perspectives, this Special Issue seeks to inspire innovation and guide the evolution of medical implants to improve the quality of life of patients around the globe.

Dr. Paolo De Angelis
Dr. Paolo Francesco Manicone
Guest Editors

Edoardo Rella
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • medical implants
  • biomaterials
  • biocompatibility
  • smart implants
  • implant design
  • personalized medicine

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

14 pages, 3978 KiB  
Article
A Novel Self-Expanding Transcatheter Mitral Valve with Dual Annulus/Valve Diameter
by Irina Yu. Zhuravleva
J. Funct. Biomater. 2025, 16(7), 250; https://doi.org/10.3390/jfb16070250 - 7 Jul 2025
Viewed by 437
Abstract
Background: The development of transcatheter mitral valves (TMVs) represents a major advancement in cardiology, driven in part by the growing elderly population. Elderly patients frequently suffer from secondary mitral regurgitation but are often ineligible for surgical valve replacement due to high procedural risks. [...] Read more.
Background: The development of transcatheter mitral valves (TMVs) represents a major advancement in cardiology, driven in part by the growing elderly population. Elderly patients frequently suffer from secondary mitral regurgitation but are often ineligible for surgical valve replacement due to high procedural risks. This study aimed to develop a self-expanding TMV stent fabricated from a single nitinol tube, featuring two distinct central zones: a smaller-diameter valve-containing segment and a larger-diameter anchoring segment for the mitral annulus. Methods: We used the COMSOL Multiphysics 6.0 software package for biotechnical engineering. Prototypes of stents and valves were manufactured in five sizes following a 22 Fr delivery system compatibility assessment and pulsatile-flow testing. Results: We bioengineered a novel stent design with an integrated porcine pericardial valve. The stents were laser-cut from nitinol tubes (4.5 mm outer diameter, 0.45 mm wall thickness) and heat-treated to achieve spatial configurations compatible with fibrous ring diameters of 40, 42, 44, 46, and 48 mm. Pericardial leaflets and coverings were then mounted onto the stents. The resulting valves were successfully loaded into a 24 Fr delivery system and exhibited proper opening and closing function under pulsatile-flow testing. Conclusions: Our findings confirm the feasibility of a single-component, dual-diameter TMV stent, offering a promising solution for high-risk patients with mitral regurgitation. Full article
(This article belongs to the Special Issue Medical Implants for Biomedical Applications)
Show Figures

Figure 1

Back to TopTop