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Clinical Applications of Echocardiographic Techniques in Cardiovascular Diagnostics

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".

Deadline for manuscript submissions: 20 September 2026 | Viewed by 728

Special Issue Editors


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Guest Editor
European Hospital, via Portuense 700, Rome, Italy
Interests: echocardiography; valvular heart disease; bicuspid aortic valve; 3D echocardiography; interventional echocardiography

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Guest Editor
Cardiovascular Imaging Department, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy
Interests: cardiac imaging; mitral valve; prolapse; mitral regurgitation; aortic stentosis; valve prosthesis; left and right ventricular function
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Special Issue Information

Dear Colleagues,

Echocardiography is a fundamental modality in the field of cardiovascular diagnostics. The technique has undergone a significant evolution, transitioning from its initial use for basic anatomical assessment to its current role as an advanced modality for detailed functional, mechanical, and hemodynamic evaluation. This progression has been driven by continuous technological innovation that has changed diagnostic and therapeutic pathways in cardiology.

This Special Issue will showcase contemporary research and expert reviews on this topic. Our aim is to assemble a collection of high-impact articles that document technological advancements and, critically, their applications in clinical decision-making and their impact on patient outcomes. This Special Issue will highlight how novel echocardiographic techniques provide clinically relevant data across a wide spectrum of cardiovascular diseases.

We look forward to receiving your submissions.

Dr. Gianpiero Italiano
Dr. Laura Fusini
Guest Editors

Manuscript Submission Information

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Keywords

  • echocardiography
  • cardiovascular diagnostics
  • 3D echocardiography
  • strain imaging
  • speckle-tracking echocardi-ography
  • valvular heart disease
  • heart failure
  • interventional echocardiography
  • stress echocardiography
  • car-dio-oncology
  • artificial intelligence

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Published Papers (1 paper)

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Research

13 pages, 499 KB  
Article
Global Longitudinal Strain Alteration of the Left Ventricle in Children with Organic Aciduria: Cardiac Disease in Organic Aciduria
by Bastien Moysset, Célia Hoebeke, Brigitte Chabrol, Guillaume Carles, Beatrice Desnous, Julie Delphine Blanc, Caroline Ovaert and Fedoua El Louali
J. Clin. Med. 2026, 15(4), 1393; https://doi.org/10.3390/jcm15041393 - 10 Feb 2026
Viewed by 407
Abstract
Introduction: Cardiac complications are well-documented in propionic acidemia (PA), and there are a few reported cases of cardiomyopathies in methylmalonic acidemia (MMA). Left-ventricular global longitudinal strain (LV GLS) measurement is known to be able to detect early ventricular dysfunction, leading potentially to cardiomyopathy. [...] Read more.
Introduction: Cardiac complications are well-documented in propionic acidemia (PA), and there are a few reported cases of cardiomyopathies in methylmalonic acidemia (MMA). Left-ventricular global longitudinal strain (LV GLS) measurement is known to be able to detect early ventricular dysfunction, leading potentially to cardiomyopathy. The aim of our study was to evaluate left-ventricular global longitudinal strain (LV GLS) in MMA and PA patients and compare it with the pediatric general population. Methods: In this monocentric retrospective study, 26 patients with organic aciduria (OA) were included. Demographic, clinical, electrocardiographic and echocardiographic data were collected. The mean LV GLS in MMA and PA patients was compared with the GLS in the pediatric general population. Results: The left-ventricular ejection fraction (LVEF) was similar between MMA and PA patients and in the normal range (66.27 ± 6.24% vs. 61.41 ± 11.02%; p = 0.182). LV GLS was significantly lower in PA patients than in MMA patients (−15.8 ± 5.67% vs. −20.6 ± 3.19%; p = 0.011). LV GLS was significantly lower in PA patients when compared with the general pediatric population (p = 0.029). Conclusions: Patients with propionic acidemia may have impaired global longitudinal strain even in the presence of normal LVEF. LV GLS might be a useful tool for cardiac follow-up in pediatric patients with OA. Full article
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