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Gastrointestinal Endoscopy: Recent Developments and Emerging Trends
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Gastrointestinal Endoscopy: Recent Developments and Emerging Trends

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".

Deadline for manuscript submissions: 30 May 2025 | Viewed by 4373

Special Issue Editors

Dr. Elia Armellini

E-Mail Website
Guest Editor
Digestive Endoscopy Unit, Asst-Bergamoest, 24068 Bergamo, Italy
Interests: interventional ultrasonography; endoscopy; NET; pancreatic cancer; EUS; endo-hepatology; ERCP
Special Issues, Collections and Topics in MDPI journals
Dr. Nico Pagano

E-Mail Website
Guest Editor
Gastroenterology Department, "Maggiore della Carità" University Hospital, Novara, Italy
Interests: gastrointestinal diseases; esophageal diseases; endoscopic retrograde cholangiopancreatography; biliary tract diseases; pancreatic diseases; endoscopy; gastrointestinal endoscopy

Special Issue Information

Dear Colleagues, 

Over the years, digestive endoscopy has evolved from a diagnostic technique to a major interventional technique both in the setting of neoplastic or preneoplastic lesions and in common benign pathologies like obesity, metabolic syndrome, or biliary tree and gallbladder lithiasis.

This evolution has changed the treatment algorithms of digestive and pancreaticobiliary diseases, giving rise to different specific applications that range from advanced resective techniques to endoscopic ultrasound-guided treatment, third space endoscopy, and bariatric endoscopy. 

This Special Issue aims to depict the progress of digestive endoscopy and offer an overview of future perspectives. Particular attention will be reserved to interventional procedures, including and welcoming case reports that describe unusual techniques or innovative ideas that may further enhance the perspectives of endoscopy. 

Reviews, systematic reviews, meta-analyses, and research papers are invited to be submitted to this Special Issue.

Dr. Elia Armellini
Dr. Nico Pagano
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • interventional ultrasonography
  • endoscopy
  • gastrointestinal endoscopy
  • NET
  • pancreatic cancer
  • EUS
  • endo-hepatology
  • ERCP

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (3 papers)

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Research

9 pages, 810 KiB  
Article
Comparison of L L Polyethylene Glycol Plus Ascorbic Acid and Oral Sodium Sulfate Tablets for Colonoscopy Bowel Preparation
by Jin Hwa Park, Minjun Kim, Seung Wook Hong, Sung Wook Hwang, Sang Hyoung Park, Dong-Hoon Yang, Byong Duk Ye, Seung-Jae Myung, Suk-Kyun Yang and Jeong-Sik Byeon
J. Clin. Med. 2024, 13(23), 7493; https://doi.org/10.3390/jcm13237493 - 9 Dec 2024
Viewed by 842
Abstract
Background and Aims: A low-volume (1 L) polyethylene glycol plus ascorbic acid (PEG-A) solution and an oral sodium sulfate tablet (OST) formulation are recently introduced agents for colonoscopy bowel preparation. This study investigated the efficacy, safety, and tolerability of 1 L PEG-A vs. [...] Read more.
Background and Aims: A low-volume (1 L) polyethylene glycol plus ascorbic acid (PEG-A) solution and an oral sodium sulfate tablet (OST) formulation are recently introduced agents for colonoscopy bowel preparation. This study investigated the efficacy, safety, and tolerability of 1 L PEG-A vs. OST. Methods: This single-center, prospective, randomized, endoscopist-blinded study randomly assigned patients into 2 groups: 1 L PEG-A (group A); and OST (group B). Efficacy of bowel preparation was evaluated using the Boston Bowel Preparation Scale (BBPS). Tolerability and safety were investigated with a standardized questionnaire. Results: A total of 174 patients were included in the final analysis (group A, n = 92; group B, n = 82). Successful bowel preparation was achieved in 91.3% and 95.1% of patients in groups A and B, respectively (p = 0.324). Overall mean satisfaction with bowel preparation was greater among those in group B vs. those in group A (8.2 ± 1.7 vs. 6.8 ± 2.0, respectively; p < 0.001). Although abdominal distension was less common in group A than group B (3/92 [3.3%] vs. 9/82 [11.0%], respectively; p = 0.045), overall adverse events developed similarly in both groups (27/92 [29.3%] vs. 21/82 [25.6%], p = 0.583). In subgroup analysis of older patients (≥65 years of age), efficacy, overall satisfaction, and safety profiles were not different between groups A and B. Conclusions: Both 1 L PEG-A and OST demonstrated efficacy, tolerability, and safety for colonoscopy bowel preparation. OST was slightly better tolerated, whereas 1 L PEG-A resulted in less abdominal distension. Both agents were effective and safe in older patients. Full article
(This article belongs to the Special Issue Gastrointestinal Endoscopy: Recent Developments and Emerging Trends)
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15 pages, 2597 KiB  
Article
Electrical Tumor Detection Probe Calibrated to Diagnose Gastrointestinal Cancer Mass in Real-Time
by Narges Yousefpour, Habibollah Mahmoodzadeh, Reihane Mahdavi, Mohammad Reza Fattahi, Amirmohsen Jalaeefar, Hossein Ataee, Fereshteh Ameli, Farzane Hajighasemi, Hadi Mokhtari Dowlatabad, Sepideh Mansouri, Omid Nabavian, Seyed Rouhollah Miri and Mohammad Abdolahad
J. Clin. Med. 2024, 13(19), 5823; https://doi.org/10.3390/jcm13195823 - 29 Sep 2024
Cited by 2 | Viewed by 1291
Abstract
Background: The primary objective of this research is to propose an intra-operative tumor detection probe calibrated on human models of gastrointestinal (G.I.) cancers, enabling real-time scanning of dissected masses. Methods: Electrical Gastrointestinal Cancer Detection (EGCD) measures impedimetric characteristics of G.I. masses [...] Read more.
Background: The primary objective of this research is to propose an intra-operative tumor detection probe calibrated on human models of gastrointestinal (G.I.) cancers, enabling real-time scanning of dissected masses. Methods: Electrical Gastrointestinal Cancer Detection (EGCD) measures impedimetric characteristics of G.I. masses using a handpiece probe and a needle-based head probe. Impedance Phase Slope (IPS) and impedance magnitude (Z1kHz) are extracted as the classification parameters. EGCD was tested on palpable G.I. masses and compared to histopathology results. Results: Calibration was carried out on 120 GI mass samples. Considering pathological results as the gold standard, most cancer masses showed Z1kHz between 100 Ω and 2500 Ω while their IPS was between −15 and −1. The EGCD total sensitivity and specificity of this categorization in G.I. cancer patients with palpable tumors were 86.4% and 74.4%, respectively (p-value < 0.01). Conclusion: EGCD scoring can be used for 3D scanning of palpable tumors in G.I. tumors during surgery, which can help clarify the tumors’ pathological response to neoadjuvant chemotherapy or the nature of intra-operative newly found G.I. tumors for the surgeon to manage their surgical procedure better. Full article
(This article belongs to the Special Issue Gastrointestinal Endoscopy: Recent Developments and Emerging Trends)
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14 pages, 1189 KiB  
Article
A Tool Integrated into the Electronic Health Record to Guide Proper Decision-Making Regarding Peri-Endoscopic Anticoagulant Management: A Retrospective Cohort Study
by Anja Plender, Suzanne E. Graumans, Eric Gielisse, Carlinda Bresser-de Ruyter, Simone Sissing, Marjan C. Ruiter-Jakobs, Arian Wals and Laura M. Faber
J. Clin. Med. 2024, 13(17), 5194; https://doi.org/10.3390/jcm13175194 - 1 Sep 2024
Cited by 1 | Viewed by 1627
Abstract
Background—Anticoagulants, such as vitamin-K antagonists (VKA) and direct oral anticoagulants (DOAC), are widely used among patients who undergo endoscopic procedures. To balance between bleeding and thromboembolic risks, careful decisions must be made about whether and for how long anticoagulants have to be [...] Read more.
Background—Anticoagulants, such as vitamin-K antagonists (VKA) and direct oral anticoagulants (DOAC), are widely used among patients who undergo endoscopic procedures. To balance between bleeding and thromboembolic risks, careful decisions must be made about whether and for how long anticoagulants have to be stopped peri-endoscopically and if bridging is necessary. We created a tool in the electronic health records system (EHR) HIX (Microsoft) for invasive procedures to aid this decision-making. By selecting the anticoagulant indication or thrombo-embolic risk and the bleeding risk of the procedure, the tool automatically generates advice for periprocedural anticoagulant management. Objectives—This study assesses whether the tool is used properly peri-endoscopically. Secondly, it examines how many bleeding and thromboembolic events have occurred since the implementation of the tool. Methods—This retrospective study included all orders placed for endoscopies for patients using VKA or DOAC between 2018 and 2021. Results—In total, 986 endoscopies were included for analysis. In 89%, the tool was used correctly; the main error was selecting the wrong bleeding risk (7.5%). The cumulative incidence for moderate or severe bleeding events for DOAC and VKA was 2 (0.5%) and 0, respectively. The cumulative incidence of thromboembolic events for DOAC and VKA was 1 (0.2%) for each. Conclusions—This study evaluates the use of an EHR-integrated decision-making tool to aid peri-endoscopic anticoagulant management. By analysing the usage of the tool, we formulated several suggestions to improve the tool. Although this study is not a comparative one, we can conclude that the thromboembolic and major bleeding risks were low. Full article
(This article belongs to the Special Issue Gastrointestinal Endoscopy: Recent Developments and Emerging Trends)
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