Diagnosis and Treatment of Salivary Gland Tumors: Current Advances and Future Options

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "General Surgery".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 710

Special Issue Editor


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Guest Editor
Department of Otorhinolaryngology, Head and Neck Surgery, Osaka Medical and Pharmaceutical University, Osaka 569-8686, Japan
Interests: salivary gland tumor; facial nerve; functional preservation; preoperative diagnosis; anticancer therapy; intraoperative nerve monitoring

Special Issue Information

Dear Colleagues,

Remarkable progress has been made in the treatment of salivary gland disease. In salivary gland tumors with a variety of histologic types, preoperative diagnosis was difficult. Advances in diagnostic imaging and cytology have made preoperative diagnosis more accurate. In addition, improvements in surgical equipment and new surgical techniques are being investigated, and methods to safely and reliably preserve the facial nerve as well as to improve treatment results are being proposed. On the other hand, since distant metastasis is not uncommon in high-grade salivary gland cancer, treatment of recurrence is also important, and new treatments such as molecular-targeted drugs have recently shown efficacy. In this Special Issue, we strongly welcome submissions of articles on clinical advances in salivary gland tumors, both diagnostic and therapeutic.

Dr. Masaaki Higashino
Guest Editor

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Keywords

  • salivary gland tumor
  • facial nerve
  • functional preservation
  • preoperative diagnosis
  • ultrasonography
  • intraoperative nerve monitoring
  • extracapsular dissection
  • endoscopic surgery
  • neck dissection
  • facial nerve reconstruction
  • anticancer therapy
  • postoperative radiation therapy
  • frey syndrome
  • first bite syndrome
  • rehabilitation

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Published Papers (1 paper)

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Research

19 pages, 19040 KiB  
Article
Comparative Diagnostic Accuracy of Ultrasound, MRI, and Fine-Needle Aspiration Biopsy in the Preoperative Evaluation of Parotid Gland Tumors
by Sebastian Stoia, Anca Ciurea, Mihaela Băciuț, Simion Bran, Gabriel Armencea, Emil Boțan, Manuela Lenghel, Tiberiu Tamaș, Rareș Mocan, Daniel Leucuța, Grigore Băciuț and Cristian Dinu
J. Clin. Med. 2025, 14(4), 1342; https://doi.org/10.3390/jcm14041342 - 18 Feb 2025
Viewed by 550
Abstract
Background: The objective of this study was to compare the value of ultrasound (US), magnetic resonance imaging (MRI), and US-guided fine-needle aspiration biopsy (FNAB) in the preoperative evaluation of parotid tumors. Methods: A three-year prospective study, including 35 patients, was conducted. Preoperative ultrasound, [...] Read more.
Background: The objective of this study was to compare the value of ultrasound (US), magnetic resonance imaging (MRI), and US-guided fine-needle aspiration biopsy (FNAB) in the preoperative evaluation of parotid tumors. Methods: A three-year prospective study, including 35 patients, was conducted. Preoperative ultrasound, MRI, and US-guided FNAB were performed on each patient, after which an imaging and cytological diagnosis was obtained. Each patient underwent surgical treatment. The imaging and cytological diagnoses were compared with the histopathological reports. Results: Ultrasound and MRI showed the same diagnostic performance in discriminating benign from malignant parotid tumors: sensitivity—80%, specificity—97%, and accuracy—94%. In this regard, FNAB registered a sensitivity, specificity, and accuracy of 100%, 97%, and 97%, respectively. US, MRI, and FNAB were recorded as having high diagnostic accuracy in the detection of pleomorphic adenoma and Warthin tumors. Conclusions: Ultrasound and US-guided FNAB allow for the preoperative differential diagnosis of parotid tumors located in the superficial lobe. When US and FNAB results are inconclusive, MRI becomes mandatory. Full article
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