New Insights into MRI Diagnosis of Retinoblastoma

Dear Colleagues, 

As many of you already know, retinoblastoma (RB) is the most common intraocular malignancy of infancy and childhood. The diagnosis is usually made by the ophthalmologist, and RB is one of the few human cancers for which treatment is generally performed without confirmed histopathology (because of the significant risk of biopsy-related tumor seeding).

Increasing eye preservation has been achieved by the introduction of conservative treatment strategies. As a consequence, more children are treated without histopathological confirmation of diagnosis or assessment of risk factors for disease dissemination and prognosis. Therefore, magnetic resonance imaging (MRI) is fundamental for evaluating tunic infiltrations, optic nerve involvement (especially when not visible at clinical examination), and extraocular spread. This Special Issue aims to present papers discussing usual and unusual types of RB, MRI protocols to be used, and associated imaging features. Papers considering the usefulness of additional sequences such as diffusion-weighted imaging (DWI) and susceptibility-weighted imaging (SWI) are also welcome, as are those discussing perspectives of perfusion and permeability imaging.

Dr. Paolo Galluzzi
Guest Editor

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• Eye
• Pediatrics
• Retinoblastoma
• Magnetic resonance imaging