Clinical Prevention and Treatment of Graft-Versus-Host Disease (GVHD)
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Hematology".
Deadline for manuscript submissions: 20 October 2025 | Viewed by 64
Special Issue Editor
Interests: graft-versus-host disease (GVHD); hematopoietic stem cell transplantation; immunosuppressive therapy; JAK inhibitors; GVHD biomarkers; transplantation complications
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Graft-versus-host disease (GVHD) is a major complication following allogeneic hematopoietic stem cell transplantation (HSCT), characterized by immune-mediated tissue damage resulting from the recipient’s immune system attacking the donor’s cells. GVHD is classified into acute and chronic forms, with both posing significant risks to patient outcomes, including morbidity, mortality, and long-term health complications. It is a critical challenge in the field of transplant medicine, particularly in the context of improving post-transplant quality of life.
Over the years, advancements in immunosuppressive therapies and post-transplant management strategies have led to a decrease in the incidence and severity of GVHD. Current treatment strategies focus on prevention, early detection, and mitigation of GVHD severity.
This Special Issue on the Clinical Prevention and Treatment of Graft-versus-host disease (GVHD) will focus on the evolving strategies in the prevention and management of GVHD, including novel immunosuppressive regimens, advances in biomarker discovery, and promising therapies. It will also explore the emerging role of post-transplant interventions aimed at reducing chronic GVHD and improving long-term patient survival and quality of life.
Dr. Roberto Crocchiolo
Guest Editor
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Keywords
- graft-versus-host disease (GVHD)
- hematopoietic stem cell transplantation
- immunosuppressive therapy
- JAK inhibitors
- GVHD biomarkers
- transplantation complications
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