Unruptured Intracranial Aneurysms: From Diagnosis to Treatment

Dear Colleagues,

As is well known, unruptured intracranial aneurysms (UIAs) represent the most frequently diagnosed vascular malformation of the brain and improvements in the availability and resolution of neuro-imaging have led to increasing incidental findings.

Post-rupture morbidity and mortality rates are still significantly high; thus, identifying and treating lesions that are more likely to rupture represent a crucial step.

However, despite the large amount of data available, factors predicting the growth or rupture of UIAs remain under debate. Even the optimum follow-up required for UIAs is yet to be fully defined because if there is a school of thought that aneurysms >7 mm in diameter should be secured either by clipping or coiling, it is unclear whether patients harbouring smaller aneurysms should also be offered treatment in the presence of other risk factors such as smoking, hypertension, abnormal morphology and family history of intracranial aneurysms.

Moreover, among patients who are treated conservatively, the most appropriate duration and frequency of imaging follow-up are unclear.

This Special Issue will identify the gaps in the diagnosis and management of UIAs based on a combination of original research and review papers.

Topics will include:

• The epidemiology of UIAs;
• Diagnostic approaches to UIAs;
• Role and frequency of follow-up;
• Interventions for UIAs.

Dr. Stefano Maria Priola
Dr. Gianluca Scalia
Dr. Giuseppe Emmanuele Umana
Dr. Vishal K. Chavda
Guest Editors

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