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Clinical Advances in Inflammatory Bowel Disease Surgery
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Clinical Advances in Inflammatory Bowel Disease Surgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".

Deadline for manuscript submissions: closed (30 November 2021) | Viewed by 2073

Special Issue Editor

Prof. Michio Itabashi

E-Mail Website
Guest Editor
Department Surgery, Institute Gastroenterol, Tokyo Women's Medical University Hospital, Shinjuku Ku, Tokyo, Japan
Interests: surgical treatment of inflammatory bowel disease

Special Issue Information

Dear Colleagues,

In recent years, medical treatment for inflammatory bowel disease has made great strides with the development of Biologics and others. Surgical treatment has also undergone various developments with the development of laparoscopic surgery.

For Crohn's disease, attempts have been made to reduce the reoperation rate by devising new anastomotic methods. In addition, the development of surveillance and appropriate treatment methods for cases with cancer is a problem. Evaluation of the patient's QOL is also an important evaluation method. I look forward to a paper on the development of surgical treatment for IBD from various perspectives.

Prof. Michio Itabashi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Inflammatory Bowel Disease
  • Ulcerative colitis
  • Crohn’s disease
  • Emergency surgery
  • Laparoscopic surgery
  • Minimally invasive surgery
  • Colitis associated cancer
  • Surgery for anal lesion of Crohn’s disease
  • Quality of life

Published Papers (1 paper)

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Research

12 pages, 3370 KiB  
Article
Possible Earlier Diagnosis of Ulcerative Colitis-Associated Neoplasia: A Retrospective Analysis of Interval Cases during Surveillance
by Takashi Hisabe, Toshiyuki Matsui, Kazutomo Yamasaki, Tsuyoshi Morokuma, Kenmei Aomi, Naoyuki Yoshizawa, Noritaka Takatsu, Kenshi Yao, Toshiharu Ueki, Kitaro Futami, Hiroshi Tanabe and Akinori Iwashita
J. Clin. Med. 2021, 10(9), 1927; https://doi.org/10.3390/jcm10091927 - 29 Apr 2021
Cited by 2 | Viewed by 1637
Abstract
Background: Early detection of ulcerative colitis-associated neoplasia (UCAN) is often difficult. The aim of this study was to clarify the morphology of initial UCAN. Methods: White-light colonoscopy images obtained within the 2 years before UCAN diagnosis were retrospectively reviewed. The primary endpoint was [...] Read more.
Background: Early detection of ulcerative colitis-associated neoplasia (UCAN) is often difficult. The aim of this study was to clarify the morphology of initial UCAN. Methods: White-light colonoscopy images obtained within the 2 years before UCAN diagnosis were retrospectively reviewed. The primary endpoint was the frequency of visible or invisible neoplasia on the endoscopic images before UCAN diagnosis. The secondary endpoints were comparisons of (1) visible or invisible neoplasia on initial endoscopic images of early-stage and advanced cancers, (2) the clinical backgrounds of patients in whom neoplasia was visible or invisible on initial endoscopic images, and (3) the clinical backgrounds of patients with distinct and indistinct UCAN borders. Results: Of the 27 UCAN lesions (11 early-stage; 16 advanced-stage), 25.9% (n = 7) were initially visible and 74.1% (n = 20) were invisible. The mean interval between the last surveillance colonoscopy and UCAN diagnosis was 14.5 ± 6.7 months. Of early-stage cancers, 18.2% (n = 2) were visible and 81.8% (n = 9) were invisible. Of advanced-stage cancers, 31.3% (n = 5) were visible and 68.8% (n = 11) were invisible. Invisible lesions were significantly more common in the rectum (p = 0.011) and tended to be more common in patients with inflammation and left-sided colitis (p = 0.084, p = 0.068, respectively). Patients with indistinct UCAN borders were significantly more likely to present with inflammation than those with distinct UCAN borders (p = 0.021). Conclusion: More careful surveillance is needed because rectum lesions and inflammation are difficult to identify as neoplasia even within the 2 years before a UCAN diagnosis. Full article
(This article belongs to the Special Issue Clinical Advances in Inflammatory Bowel Disease Surgery)
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