Journal of Clinical Medicine

Journal Browser

► Journal Browser

Advances in Prenatal Diagnosis and Maternal Fetal Medicine

Share This Special Issue

Special Issue Editors

Dr. Martina Derme

E-Mail Website
Guest Editor

Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, Roma, Italy
Interests: obstetric delivery; gynaecological surgery; ultrasound imaging; prenatal diagnosis; fetal abnormalities

Dr. Antonella Giancotti

E-Mail Website
Guest Editor

Department of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Roma, Italy
Interests: prenatal diagnosis; perinatal medicine; obstetric ultrasound; fetal abnormalities; multiple pregnancies

Special Issue Information

Dear Colleagues,

Advanced ultrasonography can be applied from the beginning of intrauterine fetal life. Prenatal diagnosis and maternal–fetal medicine are rapidly evolving. New imaging modalities and laboratory methodologies have allowed us to diagnose maternal–fetal pathologies early and therefore provide rapid treatment.

In this Special Issue, we have assembled a collection of articles from experts in maternal–fetal medicine to highlight how advances in prenatal ultrasound have caused a revolution in screening and diagnosis. Our objective is to provide an overview of the latest results achieved in this field. The spectrum of topics ranges from fetal diagnosis to genetic testing modalities and maternal–fetal medicine.

Dr. Martina Derme
Dr. Antonella Giancotti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

ultrasound imaging
prenatal diagnosis
fetal abnormalities
genetic testing
obstetric delivery

Published Papers (2 papers)

Download All Papers

Order results

Result details

Show export options Show export options

Select all

Export citation of selected articles as:

Research

Jump to: Review

10 pages, 3152 KiB

Open AccessArticle

The ‘Radiant Effect’: Recent Sonographic Image-Enhancing Technique and Its Impact on Nuchal Translucency Measurements

by Arne Bergsch, Jan Degenhardt, Rüdiger Stressig, Heiko Dudwiesus, Oliver Graupner and Jochen Ritgen

J. Clin. Med. 2024, 13(12), 3625; https://doi.org/10.3390/jcm13123625 - 20 Jun 2024

Viewed by 355

Abstract

Background: This study assesses the effects of the ‘Radiant’ image enhancement technique on fetal nuchal translucency (NT) measurements during first-trimester sonographic exams. Methods: A retrospective analysis of 263 ultrasound images of first-trimester midsagittal sections was conducted. NT measurements were obtained using a semi-automatic tool. Statistical methods were applied to compare NT measurements with and without ‘Radiant’ enhancement. An in vitro setup with predefined line distances provided additional data. Results: Incremental increases in NT measurements were observed with varying levels of ‘Radiant’ application: an average increase of 0.19 mm with ‘Radiant min’, 0.24 mm with ‘Radiant mid’, and 0.30 mm with ‘Radiant max.’ The in vitro results supported these findings, showing consistent effects on line thickness and measurement accuracy, with the smallest mean deviation occurring at the ‘Radiant mid’ setting. Conclusions: ‘Radiant’ image enhancement leads to significant increases in NT measurements. To avoid systematic biases in clinical assessments, it is advisable to disable ‘Radiant’ during NT measurement procedures. Further studies are necessary to corroborate these findings and to consider updates to the NT reference tables based on this technology. Full article

(This article belongs to the Special Issue Advances in Prenatal Diagnosis and Maternal Fetal Medicine)

► Show Figures

Figure 1

Review

Jump to: Research

20 pages, 1127 KiB

Open AccessReview

Ophthalmic Complications, Diagnosis, and Treatment of Congenital Human Cytomegalovirus Infection

by Monika Modrzejewska, Piotr Połubiński and Oliwia Zdanowska

J. Clin. Med. 2024, 13(12), 3379; https://doi.org/10.3390/jcm13123379 - 8 Jun 2024

Viewed by 968

Abstract

Background: Human cytomegalovirus (hCMV) is the most common etiological agent of congenital infections seen in newborns. Among the most commonly observed complications in children with congenital human cytomegalovirus infection are those affecting the visual system. Ocular complications of congenital CMV (cCMV) are a topic rarely addressed in the literature, which prompted the authors to update the available knowledge with the latest data. Methodology: English-language literature published between April 2000 and November 2023 (PubMed, NIH, Google Scholar) was analyzed for ocular complications of cCMV. The data obtained were categorized according to the ocular area involved and the incidence. A compilation of criteria for the symptomatic form of cCMV was also created. Results: The cCMV complications described in the literature affect all parts of the visual system: the anterior segment, the posterior segment, the posterior visual pathways, and the visual cortex. The most commonly described ocular complication of cCMV is choroidal and retinal scarring. Conclusions: Ophthalmic complications of cCMV can cause severe visual disturbances. Ophthalmic diagnosis in newborns should include hCMV PCR testing, which has the highest sensitivity and specificity. In the symptomatic form of cCMV, treatment should be instituted according to recommendations. A consensus should be established for screening of primary hCMV infection in pregnant women, the way in which to define the symptomatic form of cCMV, and the appropriateness and standards of treatment for primary hCMV infection in pregnant women. Full article

(This article belongs to the Special Issue Advances in Prenatal Diagnosis and Maternal Fetal Medicine)

► Show Figures

Figure 1

Show export options Show export options

Select all

Export citation of selected articles as:

Displaying articles 1-2

Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Title: Amniotic Band Syndrome in Monochorionic Diamniotic Twin Pregnancy: A Case Report of Fetal Swallowing of Amniotic Band
Author: Shahsavan
Highlights: This underscores the necessity of a nuanced understanding of ABS, especially in the context of MCDA twin pregnancies, where complications can be particularly intricate and unpredictable. This report contributes to the expanding body of knowledge on ABS, emphasizing its manifestations' variability and the importance of personalized care approaches in managing such rare occurrences.

Journal Menu