Advances in the Management of Aggressive Lymphomas

Dear Colleagues, 

The lymphomas are a heterogeneous group of hematologic malignancies affecting patients of all age groups and constituting approximately 4.8% of the new cancer cases in the United States. The majority of the lymphomas are considered to be clinically aggressive. While treatment for an aggressive lymphoma traditionally included upfront combination chemotherapy regimens, novel therapies are increasingly being incorporated into the treatment paradigm. Over the past two decades, the rate of death for the two most common types of aggressive lymphoma, diffuse large B-cell lymphoma and classical Hodgkin lymphoma, have declined. Rapid advances in our understanding of disease biology have resulted in the development of targeted treatments, which are largely responsible for the improvement in patient outcomes. This Special Issue will highlight treatment advances in specific aggressive lymphomas with a focus on novel therapeutics including targeted treatments, immunotherapy, and genetically modified T-cell-based therapies.

Prof. Robert A Baiocchi
Dr. Beth Christian
Guest Editors

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