Clinical Challenges in Heart Failure Management

Dear Colleagues,

Heart failure (HF) is a pandemic of the third millennium, accounting for high rates of mortality and hospitalizations. The HF burden has exposed cardiologists and hospitals to an increasing number of patients requiring treatments. For this reason, an improved approach to HF is required. The introduction of new treatments strategies, such as guanylate cyclase stimulators and myosin activators, is opening up new possibilities for HF patients to avoid adverse events. Moreover, the results of recent SGLT2i trials have opened up new treatment possibilities for HF patients with preserved ejection fraction. Besides pharmacological treatment, interesting results have been observed regarding cardiac contractility modulation (CCM) in patients with refractory symptoms, reducing the number of HF and CV deaths.  Moreover, the COVID era showed the potential of telemedicine in HF, opening the possibility of managing HF patients with virtual visits beyond classical in-person visits. In conclusion, the correct stratification of HF patients, distinguishing who needs advanced treatment strategies from those requiring palliative care, is needed in order to improve the quality of life of patients.

This Special Issue will focus on new challenges in heart failure management. Original articles, reviews of the current literature, and original perspectives on this topic will be taken into account. The Special Issue will focus on diagnostic, prognostic, and therapeutic innovations with the aim of sharing clinical experiences to improve HF patients’ management.

Dr. Paolo Severino
Dr. Gaetano M. Ruocco
Guest Editors

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