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Advanced Technologies, Concepts, and Topics in Modern Neurosurgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "General Surgery".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 970

Special Issue Editors


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Guest Editor
1. Department of Medicine, Faculty of Health, Witten/Herdecke University, 58448 Witten, Germany
2. Department of Neurosurgery, St. Barbara-Hospital, Academic Hospital of University of Muenster, 59073 Hamm, Germany
Interests: Virtual reality; Augmented reality; Image-guided surgery; Neuro-oncology; Neurovascular interventions; Skull base surgery; Spinal neurosurgery

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Guest Editor
1. Department of Medicine, Faculty of Health, Witten/Herdecke University, 58448 Witten, Germany
2. Department of Neurosurgery, St. Marien Hospitals, Academic Hospital of University of Muenster, 44534 Lünen, Germany
Interests: artificial intelligence; machine learning; robotic surgery; 3D printing; functional neurosurgery; surgical innovation

Special Issue Information

Dear Colleagues,

The field of neurosurgery is undergoing a transformative evolution driven by rapid technological advancements and interdisciplinary innovation. This Special Issue, ‘Advanced Technologies, Concepts, and Topics in Modern Neurosurgery’, aims to showcase state-of-the-art developments that are redefining neurosurgical practice across diagnostic, planning, intraoperative, and postoperative domains.

We welcome contributions that explore how modern tools such as augmented and virtual reality, intraoperative navigation systems, advanced neuroimaging, 3D printing, artificial intelligence, and surgical robotics are improving precision, minimizing invasiveness, and enhancing patient outcomes. Submissions may also focus on new paradigms in functional neurosurgery, neurovascular interventions, skull base approaches, spine surgery, neuro-oncology, and pre- and post-operative interdisciplinary patient care and complication management.

This Special Issue seeks to bridge the gap between research and clinical application by encouraging interdisciplinary collaboration among researchers and healthcare professionals from various specialties—particularly neurosurgeons, neurologists, and radiologists—as well as biomedical engineers and data scientists. Our ultimate goal is to present a comprehensive overview of where the field stands today and where it is headed, offering insights that can inspire future breakthroughs and elevate the standard of neurosurgical care worldwide.

Dr. Samer Zawy Alsofy
Dr. Ralf Stroop
Guest Editors

Manuscript Submission Information

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Keywords

  • modern neurosurgery
  • virtual reality
  • augmented reality
  • intraoperative imaging
  • neuronavigation
  • artificial intelligence
  • machine learning
  • robotic surgery
  • 3D printing
  • neurovascular interventions
  • neuro-oncology
  • skull base surgery
  • functional neurosurgery
  • spinal neurosurgery
  • surgical innovation
  • image-guided surgery
  • personalized neurosurgical planning

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Published Papers (1 paper)

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Research

17 pages, 4899 KB  
Article
Impedance Problems and Their Causes—A Single-Center Analysis of 601 Patients with De Novo Deep Brain Stimulation
by Thomas Fortmann, Samer Zawy Alsofy, Antonio Santacroce, Makoto Nakamura, Christian Ewelt and Ralph Lehrke
J. Clin. Med. 2026, 15(2), 683; https://doi.org/10.3390/jcm15020683 - 14 Jan 2026
Viewed by 638
Abstract
Background/Objectives: Patients with deep brain stimulation (DBS) require regular follow-up. When a sudden loss of therapeutic effect occurs, impedance abnormalities are often the underlying cause. If reprogramming cannot restore clinical benefit, revision surgery may be necessary to replace defective hardware. Since all [...] Read more.
Background/Objectives: Patients with deep brain stimulation (DBS) require regular follow-up. When a sudden loss of therapeutic effect occurs, impedance abnormalities are often the underlying cause. If reprogramming cannot restore clinical benefit, revision surgery may be necessary to replace defective hardware. Since all three major manufacturers are used at our center, we analyzed our patient cohort to determine the incidence and causes of impedance abnormalities. Methods: All 601 patients who underwent de novo DBS implantation in Hamm between 2009 and 2025 were evaluated for impedance abnormalities. In cases requiring revision surgery, the specific cause was identified. The manufacturer, electrodes, and contacts involved were systematically analyzed. Results: A total of 25 of 601 patients required revision surgery. Revision rates were 2.67% in patients with Parkinson’s disease, 6.19% in those with a tremor, and 5.71% in those with dystonia. Across manufacturers, 7.6% of patients with a Medtronic system required revision surgery, compared with 3.4% of patients with an Abbott system and no patients with a Boston Scientific system. The primary causes of revision were electrode-related problems (19/25), followed by extension defects (6/25), connector issues (4/25), and, in one case, a generator defect (1/25). Conclusions: Only 4.16% of patients required revision surgery due to impedance abnormalities. Patients with a tremor and non-segmented electrodes showed a higher incidence than those with Parkinson’s disease or dystonia. Predominantly older Medtronic systems had the highest revision rate, whereas no Boston Scientific systems required revision. In most cases, the electrodes were the primary source of impedance abnormalities. A total of 52% of revisions were performed within two years and 92% were performed within six years of implantation. Full article
(This article belongs to the Special Issue Advanced Technologies, Concepts, and Topics in Modern Neurosurgery)
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