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Diagnostic and Therapeutic Endoscopy in Gastroenterology: Current Advances
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Diagnostic and Therapeutic Endoscopy in Gastroenterology: Current Advances

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".

Deadline for manuscript submissions: closed (25 September 2023) | Viewed by 5631

Special Issue Editors

Prof. Dr. Deliang Liu

E-Mail Website
Guest Editor
Department of Gastroenterology, Central South University, Changsha, China
Interests: astrointestinal endoscopy; early gastrointestinal cancer; gastrointestinal precancerous lesions; gastrointestinal submucosal tumors; gastrointestinal bleeding
Dr. Yuyong Tan

E-Mail Website
Co-Guest Editor
Department of Gastroenterology, the Second Xiangya Hospital of Central South University, Changsha, China
Interests: digestive endoscopy; gastrointestinal cancer; digestive malignant tumors; fatty liver disease

Special Issue Information

Dear Colleagues,

In recent years, gastrointestinal endoscopy has endorsed mainly diagnostic and therapeutic continuous advances as a result of improvements in endoscopic technology and techniques. For diagnostic advances, the most hot topics include artificial intelligence in the diagnosis of various gastrointestinal diseases based on gastrointestinal endoscopy, endoscopic ultrasonography (EUS) and cytoendoscopy. For therapeutic advances, topics of interest include submucosal tunnel techniques (peroral endoscopic myotomy, submucosal tunneling endoscopic resection, endoscopic submucosal tunnel dissection, etc.), EUS-guided therapies (EUS-guided ablation, EUS-guided drainage, EUS-guided gastrojejunostomy, etc.), various traction methods facilitating endoscopic resection/dissection, etc. All these advances are applied more broadly in gastrointestinal adenoma, early-stage cancer, gastrointestinal motility disorders, etc.

Prof. Dr. Deliang Liu
Guest Editor
Dr. Yuyong Tan
Co-Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • artificial intelligence in gastrointestinal endoscopy
  • endoscopic ultrasonography
  • endoscopic resection/dissection
  • adenoma detection
  • early-stage gastrointestinal cancer

Published Papers (4 papers)

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Research

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12 pages, 3159 KiB  
Article
Effect of Visual Booklets to Improve Bowel Preparation in Colonoscopy: Systematic Review with Meta-Analysis
by Giuseppe Losurdo, Maria Ludovica Martino, Margherita De Bellis, Francesca Celiberto, Salvatore Rizzi, Mariabeatrice Principi, Enzo Ierardi, Andrea Iannone and Alfredo Di Leo
J. Clin. Med. 2023, 12(13), 4377; https://doi.org/10.3390/jcm12134377 - 29 Jun 2023
Viewed by 959
Abstract
An optimal bowel preparation for colonoscopy is essential to increasing the quality of the examination. Visual booklets have been proposed with conflicting results to enhance bowel preparation. A literature search was performed in March 2023 in the most important databases. Only RCTs were [...] Read more.
An optimal bowel preparation for colonoscopy is essential to increasing the quality of the examination. Visual booklets have been proposed with conflicting results to enhance bowel preparation. A literature search was performed in March 2023 in the most important databases. Only RCTs were selected. We calculated odd ratios (OR) for dichotomous outcomes. Mean differences (MD) or standardized mean differences (SMD) were used for continuous outcomes. We estimated heterogeneity with the Chi2 and the I2 statistics. In cases of high heterogeneity, a random effect model was used. Six studies were selected, enrolling 1755 patients overall. Adequate bowel preparation was observed in 86.7% of the booklet group versus 77.5% of the control group, with an OR = 2.31 in favor of the booklet. In studies using a 4-L PEG-based preparation, no difference compared to controls was observed, while in non-PEG formulations, preparation with booklets was better than in controls (OR = 5.10, 95% CI 1.82–14.27, p = 0.002). Two studies were performed in an inpatient setting without any differences between booklets and controls, while outpatients receiving booklets had better results (OR = 7.13, 95% CI 5.39–9.45, p < 0.001). The adenoma detection rate was similar between the two groups. In conclusion, booklets are useful to improve bowel preparation. Outpatient settings and preparations not containing PEG could benefit more from booklets. Full article
(This article belongs to the Special Issue Diagnostic and Therapeutic Endoscopy in Gastroenterology: Current Advances)
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11 pages, 1275 KiB  
Article
Role of Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) in the Diagnosis of Suspicious Malignant Esophageal Strictures
by Liang Min, Yumin Qing, Yi Chu, Chengbai Liang, Liang Lv, Deliang Liu, Yuyong Tan and Yuqian Zhou
J. Clin. Med. 2023, 12(6), 2153; https://doi.org/10.3390/jcm12062153 - 9 Mar 2023
Viewed by 1683
Abstract
(1) Background: The accurate diagnosis of esophageal strictures is quite critical for optimizing medical intervention. However, the diagnosis of suspicious malignant esophageal strictures with intact mucosa appearance and negative biopsy results is challenging. This study aimed to evaluate the role of endoscopic ultrasound-guided [...] Read more.
(1) Background: The accurate diagnosis of esophageal strictures is quite critical for optimizing medical intervention. However, the diagnosis of suspicious malignant esophageal strictures with intact mucosa appearance and negative biopsy results is challenging. This study aimed to evaluate the role of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) in the diagnosis of suspicious esophageal strictures. (2) Methods: We retrospectively analyzed the cases with suspicious malignant esophageal strictures that underwent EUS-FNA, with or without rapid on-site evaluation (ROSE), in our hospital from April 2017 to September 2022. Their clinical manifestations, imaging examinations, gastroscopic examinations, EUS-FNA results, and therapeutic strategies were retrospectively recorded and analyzed. (3) Results: A total of 23 patients (15 male and 8 female) were enrolled in this study. Based on EUS-FNA results, 18 patients were diagnosed with malignancies, including 16 cases of primary esophageal cancer (13 squamous carcinomas and 3 adenocarcinomas), 1 case of mediastinal cancer, and 1 case of metastatic esophageal cancer; 1 case of tuberculosis was also confirmed by EUS-FNA. Among 4 cases of ambiguous diagnosis with EUS-FNA, 1 was diagnosed with an esophageal glomus tumor after surgical removal, and 2 patients survived for several years without medical intervention, which hinted at the possibility of benign esophageal strictures. No major complications, including bleeding or perforation, were observed. (4) Conclusions: EUS-FNA may serve as a safe and effective diagnostic tool in suspicious malignant esophageal strictures with accurate specimen acquisition, especially for biopsy-negative cases. Full article
(This article belongs to the Special Issue Diagnostic and Therapeutic Endoscopy in Gastroenterology: Current Advances)
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Review

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14 pages, 530 KiB  
Review
Third Eye? The Assistance of Artificial Intelligence (AI) in the Endoscopy of Gastrointestinal Neoplasms
by Magdalena Leśniewska, Rafał Patryn, Agnieszka Kopystecka, Ilona Kozioł and Julia Budzyńska
J. Clin. Med. 2023, 12(21), 6721; https://doi.org/10.3390/jcm12216721 - 24 Oct 2023
Cited by 2 | Viewed by 1390
Abstract
Gastrointestinal cancers are characterized by high incidence and mortality. However, there are well-established methods of screening. The endoscopy exam provides the macroscopical image and enables harvesting the tissue samples for further histopathological diagnosis. The efficiency of endoscopies relies not only on proper patient [...] Read more.
Gastrointestinal cancers are characterized by high incidence and mortality. However, there are well-established methods of screening. The endoscopy exam provides the macroscopical image and enables harvesting the tissue samples for further histopathological diagnosis. The efficiency of endoscopies relies not only on proper patient preparation, but also on the skills of the personnel conducting the exam. In recent years, a number of reports concerning the application of artificial intelligence (AI) in medicine have arisen. Numerous studies aimed to assess the utility of deep learning/ neural network systems supporting endoscopies. In this review, we summarized the most recent reports and randomized clinical trials regarding the application of AI in screening and surveillance of gastrointestinal cancers among patients suffering from esophageal, gastric, and colorectal cancer, along with the advantages, limitations, and controversies of those novel solutions. Full article
(This article belongs to the Special Issue Diagnostic and Therapeutic Endoscopy in Gastroenterology: Current Advances)
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Other

Jump to: Research, Review

6 pages, 576 KiB  
Brief Report
Can Ampullary G1 and G2 Neuroendocrine Tumors Be Cured by Endoscopic Papillectomy?
by Wengang Zhang, Ningli Chai and Enqiang Linghu
J. Clin. Med. 2023, 12(6), 2286; https://doi.org/10.3390/jcm12062286 - 15 Mar 2023
Cited by 2 | Viewed by 919
Abstract
Objectives: At present, pancreaticoduodenectomy or local excision are the main treatment options for ampullary neuroendocrine tumors of any size with no distant spread. Endoscopic papillectomy provided a super minimally invasive treatment method for ampullary lesions. However, the studies of endoscopic papillectomy for ampullary [...] Read more.
Objectives: At present, pancreaticoduodenectomy or local excision are the main treatment options for ampullary neuroendocrine tumors of any size with no distant spread. Endoscopic papillectomy provided a super minimally invasive treatment method for ampullary lesions. However, the studies of endoscopic papillectomy for ampullary neuroendocrine tumors were very limited. This study aimed to assess the feasibility of endoscopic papillectomy for ampullary neuroendocrine tumors. Methods: Between August 2007 and June 2021, seven patients with ampullary neuroendocrine tumors with no advanced signs underwent endoscopic papillectomy in our center. We assessed and analyzed the related clinical outcomes. Moreover, a comprehensive literature review was conducted. Results: All the seven cases underwent endoscopic papillectomy successfully; six (85.7%) of them achieved the complete resection. No recurrence occurred over a median follow-up of 48 months (range 6–172 months). Moreover, 22 cases from the comprehensive search were included, and showed a promising clinical outcome. Conclusions: Endoscopic papillectomy appeared to be a feasible way to treat ampullary neuroendocrine tumors without the advanced signs, although further prospectively multicenter studies are warranted. Full article
(This article belongs to the Special Issue Diagnostic and Therapeutic Endoscopy in Gastroenterology: Current Advances)
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