Multiple Myeloma: Advances in Diagnosis and Treatment
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Oncology".
Deadline for manuscript submissions: 25 July 2025 | Viewed by 1735
Special Issue Editor
2. Faculty of Medicine, University of Basel, Klingelbergstrasse 61, 4056 Basel, Switzerland
Interests: multiple myeloma; bood and marrow transplantation; hematology; hematopoietic cell transplantation; Waldenström’s macroglobulinemia; AL amyloidosis; liver cancer; meta-analysis; immunotherapy
Special Issue Information
Dear Colleagues,
Multiple myeloma is characterized as a complex hematological malignancy with abnormal plasma cell proliferation. During the last decade, remarkable advances in the diagnosis and treatment of multiple myeloma have been made. Due to increased understandings of the pathogensis of multiple myeloma, including clonal evolution, its microenviroment, the role of circulating cells and the innovation of diagnostic techniques, significant developments in detecting and monitoring multiple myeloma could be observed in the near future. Though advances in multiple myeloma could be achieved and translated into improved patients outcomes, ongoing research efforts are focusing on the treatment of relapsed/refractory multiple myeloma patients to explore novel therapeutic agents such as chimeric antigen reseptor (CAR), T-cell therapy, or bispecific T-cell engager (BiTE) treatment modalities and their mechanisms of resistance. In parallel, the exploration of non-immune therapy options in replased/refactory multiple myeloma and combination therapies to optimize therapy efficacy and adverse effects will hopefully expand the availability of therapies for multiple myeloma patients. Not only the treatment of refractory/relapsed myeloma, but also the extent to which precursor conditions such as MGUS or smoldering myeloma need to be treated, are topics for further analysis, which could greatly improve the current landscape of plasma cell dyscrasias.
We look forward to receiving your submissions.
Dr. Martina Kleber
Guest Editor
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Keywords
- multiple myeloma
- early intervention
- novel therapies
- treatment approach
- prognosis
- bispecific antibodies
- CAR T-cells
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