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Latest Advances and Clinical Applications of Endoscopic Technology
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Latest Advances and Clinical Applications of Endoscopic Technology

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".

Deadline for manuscript submissions: closed (31 March 2025) | Viewed by 1339

Special Issue Editors

Dr. Cecilia Binda

E-Mail Website
Guest Editor
Gastroenterology and Digestive Endoscopy Unit, Forlì-Cesena Hospitals, AUSL Romagna, Forlì, Forlì-Cesena, Italy
Interests: interventional endoscopy; EUS; ERCP; interventional EUS; biliopancreatic diseases; pancreatic cancer; cholangiocarcinoma
Special Issues, Collections and Topics in MDPI journals
Dr. Giulia Gibiino

E-Mail Website
Guest Editor
Gastroenterology and Digestive Endoscopy Unit, Ospedale Morgagni-Pierantoni, Forlì-Ospedale M. Bufalini, Cesena-AUSL, 47521 Forlì, Romagna, Italy
Interests: interventional endoscopy; ESD; EMR; microbiota; colorectal cancer; gastric cancer

Special Issue Information

Dear Colleagues,

New technologies and devices are proposed every day in the field of diagnostic and therapeutic digestive endoscopy. In the former, artificial intelligence software and HD instruments provide increasingly accurate and real-time diagnosis. In the therapeutic approach, innovative techniques and devices are introduced to obtain the best therapeutic response by reducing the limitations and risks of the usual procedures. This applies, for example, to traction techniques and devices that facilitate advanced resections as well as dedicated accessories for advanced therapeutic endoscopic ultrasound (EUS) procedures. Innovation must always be aimed at ensuring better clinical outcomes.

Therefore, we are proposing a Special Issue entitled “Latest Advances and Clinical Applications of Endoscopic Technology” dedicated to the most recent research on endoscopic technology.

It is our pleasure to invite you to contribute this Special Issue with original contributions, systematic reviews and pilot studies on endoscopic technology and the most recent advances in endoscopy, such as in diagnostic upper and lower gastrointestinal endoscopy, endoscopic resection of neoplastic lesions, diagnostic and therapeutic endoscopic ultrasound (EUS), cholangioscopy and endoscopic retrograde cholangio-pancreatography (ERCP).

We look forward to receiving your contributions.

Dr. Cecilia Binda
Dr. Giulia Gibiino
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • interventional endoscopy
  • EUS
  • ERCP
  • ESD
  • artificial intelligence
  • bariatric endoscopy
  • third space endoscopy
  • therapeutic endoscopy

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

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10 pages, 1126 KB  
Article
Endoscopic Use of N-Butyl-2-Cyanoacrylate in Refractory Pancreatic Duct Leak and Cystic Duct Leak: Is It Really a Last Resort?
by Mario Gagliardi, Carlo Soldaini, Mariano Sica, Carmela Abbatiello, Michele Fusco, Federica Fimiano, Giuseppina Pontillo, Elio Donnarumma, Alessandro Puzziello and Claudio Zulli
J. Clin. Med. 2025, 14(10), 3362; https://doi.org/10.3390/jcm14103362 - 12 May 2025
Viewed by 515
Abstract
Background/Objectives: The management of refractory pancreatic duct (PD) and cystic duct leaks may represent an endoscopic challenge. Standard endoscopic therapy involves pancreatic/biliary sphincterotomy and stenting during endoscopic retrograde cholangiopancreatography (ERCP). After conservative (fasting, parenteral nutrition, and use of somatostatin analogs) or conventional [...] Read more.
Background/Objectives: The management of refractory pancreatic duct (PD) and cystic duct leaks may represent an endoscopic challenge. Standard endoscopic therapy involves pancreatic/biliary sphincterotomy and stenting during endoscopic retrograde cholangiopancreatography (ERCP). After conservative (fasting, parenteral nutrition, and use of somatostatin analogs) or conventional endoscopic treatments fail, a surgical approach is usually required, leading to higher mortality due to several technical complications. Previous evidence of the endoscopic use of N-butyl-2-cyanoacylate (NBCA) for treating pancreaticobiliary leaks is reported, although the evidence is scarce. Methods: Six patients with pancreaticobiliary leaks (three IT pancreatic leaks and three Class A sec. Strasberg post-cholecystectomy biliary leaks) refractory to previous treatment were treated with the endoscopic topical application of NBCA. All our patients gave informed consent. The procedures were all performed between December 2017 and February 2025 at a tertiary referral center for biliopancreatic endoscopy. Results: Therapeutic success, as shown both endoscopically and radiologically, was 100%, and no procedural complication was reported. In one patient with biliary leak, standard cannulation of the cystic duct stump with the guidewire was unsuccessful, requiring a peroral cholangioscopy (SpyGlass System DSII) to directly visualize the leakage site, allowing a precise closure of the wall defect with NBCA. Conclusions: NBCA injection could represent a safe and effective endoscopic option in refractory PD of the tail of the pancreas and cystic duct leaks. Larger and further studies are necessary to confirm these results. Full article
(This article belongs to the Special Issue Latest Advances and Clinical Applications of Endoscopic Technology)
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Review

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10 pages, 354 KB  
Review
Resect and Retrieve Colorectal Polyps: Time for New Insights
by Giulia Gibiino, Cecilia Binda, Matteo Secco, Lorenzo Cosentino, Francesco Poggioli, Stefania Cappetta, Davide Trama, Andrea Fabbri, Chiara Coluccio and Carlo Fabbri
J. Clin. Med. 2025, 14(16), 5846; https://doi.org/10.3390/jcm14165846 - 18 Aug 2025
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Abstract
Polyp retrieval following colorectal polypectomy remains a critical step for histopathological analysis and determining appropriate surveillance intervals. Despite reported retrieval rates exceeding 90% in the literature, significant heterogeneity persists in clinical practice, particularly for polyps < 10 mm, due to the lack of [...] Read more.
Polyp retrieval following colorectal polypectomy remains a critical step for histopathological analysis and determining appropriate surveillance intervals. Despite reported retrieval rates exceeding 90% in the literature, significant heterogeneity persists in clinical practice, particularly for polyps < 10 mm, due to the lack of standardized retrieval methods. This review synthesizes current evidence on polyp retrieval techniques, the impact of lesion size, and device-specific considerations, including suction-based methods, retrieval nets, and other approaches such as the water-bolus and water-slider techniques. We also examine the clinical utility and limitations of the “resect and discard” and “diagnose and leave in situ” strategies, highlighting barriers to widespread implementation such as medico-legal risks, variability in optical diagnosis, and discrepancies across international guidelines. The integration of advanced imaging technologies, including high-definition endoscopy, virtual chromoendoscopy, and artificial intelligence-driven computer-aided diagnosis (CADx), represent promising tools to help in increasing the diagnostic accuracy of diminutive polyps. As post-polypectomy surveillance recommendations remain tethered to histological findings, this review underlines the need for updated, evidence-based frameworks that take into account technological advancements while ensuring diagnostic precision, cost-effectiveness, and patient safety in colorectal cancer prevention. Full article
(This article belongs to the Special Issue Latest Advances and Clinical Applications of Endoscopic Technology)
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