Clinical Therapeutic Advances in Bone Fractures

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: 10 July 2025 | Viewed by 1109

Special Issue Editors


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Guest Editor
Department of Trauma Surgery, BG Unfallklinik Murnau, Professor-Küntscher-Str. 8, 82418, Murnau am Staffelsee, Germany
Interests: fracture-related infection; nonunion; low-grade infection; bone defect management; osteomyelitis; soft tissue infec-tion; long-bone fractures

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Guest Editor
1. Department of Orthopedic and Trauma Surgery, BG Klinikum Duisburg, University of Duisburg-Essen, Großenbaumer Allee 250, 47249, Duisburg, Germany
2. Department of Trauma, Hand and Reconstructive Surgery, University Hospital Duisburg-Essen, Essen, Germany
Interests: osteomyelitis; fracture-related infection; non-union; bone substitutes; bone reconstruction

Special Issue Information

Dear Colleagues,

In recent years, there have been significant therapeutic advances in the management of bone fractures, from diagnostic methods to the ongoing optimization of fracture healing, as well as the rehabilitation of patients returning to work. It is the surgeon's responsibility to incorporate new findings and their combination into daily treatment to achieve optimal treatment results.

This Special Issue on “Clinical Therapeutic Advances in Bone Fractures” is dedicated to showcasing innovations in the treatment of bone fractures. These approaches to bone repair include biological methods such as bone morphogenetic proteins or stem cells, as well as orthobiologics like bone substitutes that provide scaffolding for new bone formation and aid in fracture stabilization. Additionally, biomechanical enhancements, minimally invasive surgical techniques, and enhanced rehabilitation protocols can optimize functional recovery and prevent complications such as fracture-related infections, nonunion, and functional deficits. Furthermore, the utilization of molecular diagnostics and technological innovations such as 3D printing for the creation of patient-specific implants and scaffolds allows clinicians to improve the precision and effectiveness of fracture fixation and bone regeneration.

This Special Issue of the Journal of Clinical Medicine aims to enhance the diagnosis and treatment of bone fractures, as well as the management of their complications, through scientific recommendations. The goal is to improve daily clinical practice and benefit patients.

Dr. Simon Hackl
Dr. Eva Simone Steinhausen
Guest Editors

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Keywords

  • stem cells
  • biomechanics
  • fracture fixation
  • orthobiologics
  • rehabilitation
  • personalized medicine
  • 3D printing
  • im-plant coating
  • nonunion
  • fracture-related infection

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Published Papers (1 paper)

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Research

11 pages, 1444 KiB  
Article
Mapping of Patellar Fracture Patterns: A Multicenter Study of 237 Patients
by Julia Elisabeth Lenz, Amadeus Dominik Schraag, Luis Plank, Christian von Rüden, Volker Alt and Johannes Weber
J. Clin. Med. 2025, 14(4), 1335; https://doi.org/10.3390/jcm14041335 - 17 Feb 2025
Viewed by 547
Abstract
Background/Objectives: Patellar fractures are rare but clinically significant due to their impact on knee function. These injuries vary from simple transverse to complex comminuted patterns. Computed tomography (CT) offers superior visualization compared to radiographs, enabling accurate classification and surgical planning. This study utilized [...] Read more.
Background/Objectives: Patellar fractures are rare but clinically significant due to their impact on knee function. These injuries vary from simple transverse to complex comminuted patterns. Computed tomography (CT) offers superior visualization compared to radiographs, enabling accurate classification and surgical planning. This study utilized CT-based fracture mapping to analyze fracture patterns and evaluate the impact of age, trauma-center level, and AO/OTA classification. Methods: This retrospective study included 237 patients diagnosed with patellar fractures who underwent CT imaging. Fractures were classified using the AO/OTA system, and fracture mapping was performed by overlaying fracture lines onto a standardized template. Statistical analysis assessed correlations between patient demographics, trauma-center level, and fracture patterns. Results: The cohort comprised 107 males and 130 females with a mean age of 56.9 ± 20.9 years. Males were significantly younger than females (49.2 vs. 63.3 years, p < 0.001). Fractures were evenly distributed between the right (46%) and left (54%) patellae. Type C fractures were the most common (54.4%), followed by Type B (29.9%) and Type A (15.6%). Trauma-center level was inversely associated with fracture severity (p < 0.001), with complex fractures more common at lower-level centers. Age was positively correlated with fracture severity (p = 0.001). Fracture mapping revealed the central patella as the most frequently affected region, with transverse fractures extending medially and laterally, sparing the upper and lower poles. Conclusions: CT imaging enhances the classification and mapping of patellar fractures, highlighting the central patella as the primary site of injury. Fracture severity correlates with age and trauma-center level. These findings support CT-based mapping as a valuable tool for improving surgical planning and treatment outcomes. Full article
(This article belongs to the Special Issue Clinical Therapeutic Advances in Bone Fractures)
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