Pulmonary Embolism: The Era of Catheter-Directed Treatment
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Respiratory Medicine".
Deadline for manuscript submissions: closed (24 May 2024) | Viewed by 10849
Special Issue Editors
Interests: catheter directed tratment in pulmonary embolism; TAVR; complex coronary interventions; chronic total occlusion; acute coronary syndrome
Interests: complex coronary interventions; chronic total occlusion recanalisation; intracoronary imaging; left ventricle mechanical support devices
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Special Issue Information
Dear Colleagues,
Catheter-directed treatments (CDTs) consist of a series of catheter-based techniques used to obtain pulmonary vessel reperfusion in acute pulmonary embolism (PE).
According to international guidelines, CDTs should be the considered as a first-line treatment in high-risk PE patients in whom systemic thrombolysis (ST) is contraindicated or has failed, and as bailout in case of hemodynamic decompensation in anticoagulant therapy in intermediate–high-risk patients.
However, due to limited scientific evidence in this field and the absence of randomized clinical trials against the standard of care, CDTs have limited diffusion and a significant proportion of high-risk and intermediate–high-risk PE patients represent an area of unmet clinical need, with high mortality due to PE consequences if left untreated, and high bleeding risk if treatment is attempted.
In this scenario, there is a growing clinical and scientific interest in CDTs because they could tackle some unresolved issues targeting the treatment of pulmonary arteries and avoiding the dreaded complication of ST.
Several areas in this field need to be further assessed, including the definition of treatment failure or the long-term effect of CDTs.
The aim of this Special Issue is to gather evidence regarding the currently available CDT approaches in PE patients, patient selection, and the timing and techniques of the procedure.
Dr. Filippo Russo
Dr. Mario Iannaccone
Guest Editors
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Keywords
- pulmonary embolism
- catheter-directed treatment
- catheter-directed thrombolysis
- thrombus aspiration for pulmonary embolism
- PERT
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