Redefining Hemodialysis: Beyond Diffusion to Precision Therapy
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Nephrology & Urology".
Deadline for manuscript submissions: 15 August 2026 | Viewed by 1210
Special Issue Editors
Interests: hemodialysis; dialysis; balanced scorecard; strategy; nephrology; management; hypertension; diabetes; doppler; supply chain management; internal medicine; blood pressure; renal disease
Interests: acute kidney injury; AI, atrial natriuretic factor; calciphylaxis; cardiovascular surgical procedures; diuretics; hospitalists; hyponatremia; kidney failure, chronic; natriuretic peptides; referral and consultation; renal dialysis; renal insufficiency, chronic; thiosulfates; uremia; vascular calcification
Special Issue Information
Dear Colleagues,
Despite major technological progress, hemodialysis continues to be associated with high mortality, frequent hospitalization, and a persistent burden of cardiovascular, inflammatory, metabolic, and cognitive complications. Diffusion-centered therapies are no longer sufficient to address the complexity of advanced kidney failure, characterized by middle- and larger-molecular-weight toxin accumulation, chronic inflammation, fluid overload, oxidative stress, endothelial dysfunction, and hemodynamic instability.
This Special Issue, “Redefining Hemodialysis: Beyond Diffusion to Precision Therapy”, will highlight innovative, physiology-driven strategies to transform dialysis into a more effective, personalized, and outcome-orientated therapy. Areas of interest include optimized convective clearance, advances in membrane and adsorption technologies, individualized fluid management, the targeted modulation of inflammation and oxidative stress, and improved gas-exchange strategies to reduce dialysis-induced hypoxia.
We also welcome contributions integrating digitalization, artificial intelligence, digital biomarkers, and machine-learning-based risk prediction to support adaptive prescriptions and continuously tailored treatments. Furthermore, we encourage research advancing environmentally sustainable models—green dialysis—and modern evidence-generation frameworks such as novel clinical trial designs and clinical trial emulation.
Our aim in launching this Special Issue is a bold and necessary one: to elevate hemodialysis from a life-sustaining intervention to a precision-based, patient-centered, and outcome-driven therapy.
Dr. Stefano Stuard
Dr. Sagar Nigwekar
Guest Editors
Manuscript Submission Information
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Keywords
- digitalized medical governance
- precision dialysis
- convective clearance
- advanced membranes
- hemodynamic stability
- artificial intelligence
- digital biomarkers
- personalized prescription
- cardiovascular protection
- patient-reported outcome measures
- clinical trial emulation
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