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Clinical Innovation in Endoscopic Sinus and Anterior Skull Base Surgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Otolaryngology".

Deadline for manuscript submissions: 15 May 2026 | Viewed by 457

Special Issue Editors


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Guest Editor
1. South West Neurosurgery Centre, University Hospitals Plymouth NHS Trust, Derriford Hsopital, Plymouth, UK
2. Peninsula Medical School, University of Plymouth, Plymouth, UK
Interests: skull base and pituitary surgery; neuro-endocoscopy; surgical simulation

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Guest Editor
1. ENT Department, University Hospitals Plymouth NHS Trust, Plymouth, UK
2. Peninsula Medical School, University of Plymouth, Plymouth, UK
Interests: rhinology; endoscopic sinus surgery; anterior skull base surgery; surgical simulation

Special Issue Information

Dear Colleagues,

The Special Issue titled "Clinical Innovation in Endoscopic Sinus and Anterior Skull Base Surgery" delves into the latest advancements, techniques, and technologies that are transforming this field. It also focuses on complex case management, strategies for mitigating complications, and emerging therapeutic options for sinonasal and skull base conditions. We invite contributions that offer insights into evidence-based practices, interdisciplinary collaboration, novel techniques, and future directions in endoscopic sinus and anterior skull base surgery.

Dr. Samiul Muquit
Dr. Marios Stavrakas
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • rhinology
  • endoscopic anterior skull base surgery
  • anterior skull base surgery
  • endoscopic sinus surgery
  • chronic rhinosinusitis (CRS)
  • otolaryngology

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Published Papers (1 paper)

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Research

12 pages, 1065 KB  
Article
Factors Influencing Outcome After Frontal Beak Reduction—Does the Surgical Tool Matter?
by Łukasz Skrzypiec, Kornel Szczygielski, Dariusz Jurkiewicz and Marta Aleksandra Kwiatkowska
J. Clin. Med. 2025, 14(23), 8377; https://doi.org/10.3390/jcm14238377 - 26 Nov 2025
Viewed by 217
Abstract
Introduction: Chronic rhinosinusitis (CRS) with frontal sinus outflow tract (FSOT) obstruction frequently requires frontal beak reduction during endoscopic sinus surgery (ESS). While technical approaches such as rotary drilling or piezoelectric osteotomy may differ in precision and tissue preservation, it is unclear whether [...] Read more.
Introduction: Chronic rhinosinusitis (CRS) with frontal sinus outflow tract (FSOT) obstruction frequently requires frontal beak reduction during endoscopic sinus surgery (ESS). While technical approaches such as rotary drilling or piezoelectric osteotomy may differ in precision and tissue preservation, it is unclear whether surgical instrument choice or patient-specific clinical characteristics influence postoperative quality of life (QoL). Methods: In this prospective cohort study, 49 adult CRS patients undergoing ESS with frontal beak reduction were enrolled (28 males, mean age 50 ± 15 years). Osteotomy was performed using either a conventional drill (n = 25) or piezoelectric knife (n = 24). Baseline clinical data included presence of nasal polyps, asthma, and radiologic severity (Lund–Mackay and Zinreich CT scores). Outcomes included patient-reported symptoms with the 22-item Sino-Nasal Outcome Test (SNOT-22) and visual analogue scale (VAS), and endoscopic Lund–Kennedy scores, recorded preoperatively and at 1, 4, and 24 weeks postoperatively. Results: Both groups demonstrated significant postoperative improvement in SNOT-22 and VAS scores. No significant correlation was observed between SNOT-22 changes and Lund–Kennedy scores in either tool group. Presence of nasal polyps was associated with higher pre- and postoperative Zinreich and Lund–Mackay scores (p < 0.05). Asthma was linked to higher early postoperative symptom burden (nasal blockage, clear discharge; p < 0.05). Tool choice did not significantly influence QoL recovery or modify the effect of clinical characteristics on outcomes. Conclusions: Postoperative QoL improvement was driven primarily by baseline disease phenotype—particularly nasal polyposis and asthma—while the choice of osteotomy instrument did not significantly influence recovery trajectories. The Zinreich score provided additional phenotypic stratification in CRS with FSOT obstruction. Full article
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