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Innovative Technologies and Approaches in Eye Disease Management and Refractive Surgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Ophthalmology".

Deadline for manuscript submissions: 25 May 2026 | Viewed by 1494

Special Issue Editor


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Guest Editor
Department of Ophthalmology, School of Medicine, Keio University, Tokyo, Japan
Interests: multifocal intraocular lenses; femtosecond lasers; artificial intelligence; telemedicine; medical devices; imaging
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, in the field of eye disease management and refractive surgery, innovative technologies and approaches have been introduced to medical devices. With this, the current Special Issue will feature reports on the latest information regarding eye surgery hardware and software. Specifically, it will focus on the following topics:

  1. Improved vision with the introduction of multifocal intraocular lenses.

The use of multifocal intraocular lenses is becoming more common in cataract surgery. These lenses provide bifocal vision and improve visual convenience in patients' daily lives. However, they are not suitable for all patients, and individual adaptation tests and thorough consultation with doctors are important.

  1. Progress in minimally invasive surgical techniques.

The introduction of the latest technologies, such as femtosecond lasers and 3D imaging systems, has improved the accuracy of surgery and reduced the burden on patients. These technologies also contribute to shortening surgery times and accelerating postoperative recovery.

  1. Artificial intelligence (AI) in eye diseases.

AI has brought about great advances in diagnosis, treatment, and patient management in the field of ophthalmology. Its use is particularly advancing image diagnosis, the optimization of surgical plans, and the development of telemedicine; in the future it is expected to be applied to further improve accuracy and personalized medicine. However, AI is merely an auxiliary tool, and it is important to maximize its effectiveness by working together with ophthalmologists.

These technologies and approaches are improving the quality of eye care and contributing to improved visual health and quality of life for patients. We look forward to your contributions.

Dr. Hidenaga Kobashi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • multifocal intraocular lenses
  • femtosecond lasers
  • artificial intelligence
  • imaging
  • eye surgery
  • refractive surgery

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Published Papers (1 paper)

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Research

14 pages, 2326 KB  
Article
Enhancing Safety in Refractive Surgery: A Pilot Evaluation of In Vivo Confocal Microscopy
by Dominika Janiszewska-Bil, Magdalena Kijonka, Joanna Kokot-Lesiuk, Victor Derhartunian, Anita Lyssek-Boroń, Dariusz Dobrowolski, Edward Wylęgała, Beniamin Oskar Grabarek and Katarzyna Krysik
J. Clin. Med. 2025, 14(21), 7714; https://doi.org/10.3390/jcm14217714 - 30 Oct 2025
Viewed by 374
Abstract
Background: In vivo confocal microscopy (IVCM) provides high-resolution corneal imaging that may enhance preoperative and postoperative assessment in refractive surgery. This pilot study aimed to evaluate the diagnostic utility of IVCM in identifying subclinical corneal abnormalities that could influence surgical qualification and outcomes. [...] Read more.
Background: In vivo confocal microscopy (IVCM) provides high-resolution corneal imaging that may enhance preoperative and postoperative assessment in refractive surgery. This pilot study aimed to evaluate the diagnostic utility of IVCM in identifying subclinical corneal abnormalities that could influence surgical qualification and outcomes. Methods: A total of 7 patients (3 males, 4 females; mean age 48.8 ± 14.5 years) undergoing qualification or follow-up for refractive surgery were prospectively examined between May 2021 and March 2025. Each participant underwent a comprehensive ophthalmic evaluation, including slit-lamp biomicroscopy, corneal topography, anterior segment optical coherence tomography (AS-OCT), and IVCM using the Heidelberg Retina Tomograph II with Rostock Cornea Module. Patients with prior ocular surgery, active infection, or systemic corneal disease were excluded. Results: IVCM revealed subtle epithelial, stromal, and endothelial abnormalities undetectable by conventional methods. Findings such as Thygeson’s keratitis, pre-Descemet’s dystrophy, and subclinical herpes simplex keratitis led to modifications of surgical plans or disqualification in selected cases. The technique also aided postoperative evaluation of epithelial–stromal interface disorders. Conclusions: IVCM proved to be a valuable adjunct in detecting subclinical corneal pathology, refining patient selection, and improving safety in refractive surgery. Larger multicenter studies are warranted to validate its clinical role and define standardized indications for preoperative screening. Full article
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