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Special Issue "Insecticide Resistance: Challenge to Pest Management and Basic Research"

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A special issue of Insects (ISSN 2075-4450). This special issue belongs to the section "Insect Pest and Vector Management".

Deadline for manuscript submissions: 28 May 2023 | Viewed by 4511

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Special Issue Editor

Dr. Shun-fan Wu

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Guest Editor

Laboratory of Bio-Interactions and Crop Health, College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China
Interests: insecticide resistance; insecticide toxicology; cytochrome P450s; target-site insensitivity; insect growth regulator; novel insecticides targets

Special Issue Information

Dear Colleagues,

Insecticide resistance is a serious problem affecting the efficacy and utility of compounds. It is exhausting our agricultural arsenal against pests. Scientists are engaged in investigating the mechanisms by which insects develop resistance to insecticides, such as target-protein resistance, metabolic resistance, cuticular resistance and increased transporter activity, which leads to the excretion of insecticide from the pest. This Special Issue will report recent, innovative tools and reviews on specific subject areas related to insecticide resistance mechanisms and insecticide resistance management strategies.

Dr. Shun-fan Wu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Insects is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

insecticide resistance
insecticide toxicology
cytochrome P450s
target-site insensitivity
insect growth regulator
novel insecticides targets

Published Papers (4 papers)

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Research

Open AccessArticle

Alpha-Cypermethrin Resistance in Musca domestica: Resistance Instability, Realized Heritability, Risk Assessment, and Insecticide Cross-Resistance

Naeem Abbas

and

Abdulwahab M. Hafez

Insects 2023, 14(3), 233; https://doi.org/10.3390/insects14030233 - 26 Feb 2023

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Abstract

Musca domestica L., the common house fly, is a cosmopolitan carrier of human and livestock disease pathogens. The species exhibits resistance to many insecticides; therefore, effective M. domestica insecticide resistance management programs are required worldwide. In the present study, the development of alpha-cypermethrin resistance, realized heritability (h²), instability of resistance trait (DR), and cross-resistance (CR) was investigated in an alpha-cypermethrin-selected M. domestica strain (Alpha-Sel) across 24 generations (Gs). Compared with an alpha-cypermethrin-unselected strain (Alpha-Unsel), resistance to alpha-cypermethrin increased from 46.4-fold (G₅) to 474.2-fold (G₂₄) in Alpha-Sel females and 41.0-fold (G₅) to 253.2-fold (G₂₄) in Alpha-Sel males. Alpha-cypermethrin resistance declined by between –0.10 (G₅) and –0.05 (G₂₄) in both M. domestica sexes without insecticide exposure for 24 generations. The h² of alpha-cypermethrin resistance was 0.17 and 0.18 for males and females, respectively, in G₁–G₂₄. With selection intensities of 10–90%, the G values required for a tenfold increase in the LC₅₀ of alpha-cypermethrin were 6.3–53.7, 4.1–33.8, and 3.0–24.7, given h² values of 0.17, 0.27, and 0.37, respectively, and a constant slope of 2.1 for males and h² values of 0.18, 0.28, and 0.38, respectively, and a constant slope of 2.0 for females. Compared with Alpha-Unsel, Alpha-Sel M. domestica exhibited moderate CR to bifenthrin (15.5-fold), deltamethrin (28.4-fold), and cyfluthrin (16.8-fold), low CR to two pyrethroids and five organophosphates, and no CR to insect growth regulators. The instability of resistance trait, low h², and absent or low CR associated with alpha-cypermethrin resistance in M. domestica indicate resistance could be managed with rotational use of the insecticide. Full article

(This article belongs to the Special Issue Insecticide Resistance: Challenge to Pest Management and Basic Research)

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Open AccessArticle

Spatial Distribution of Pyrethroid Resistance and kdr Mutations in Aedes aegypti from La Guajira, Colombia

Ronald Maestre-Serrano

Zulibeth Flórez-Rivadeneira

Juan M. Castro-Camacho

Alan E. Juache-Villagrana

and

Adriana E. Flores

Insects 2023, 14(1), 31; https://doi.org/10.3390/insects14010031 - 29 Dec 2022

Viewed by 1380

Abstract

Dengue, chikungunya, and Zika are of great concern to the public health of Colombia. One of the main control strategies for these diseases is the application of insecticides directed at the Aedes aegypti vector. However, insecticide resistance has been increasingly recorded in the country, making control measures difficult. Here, we evaluated the resistance profiles for pyrethroids in populations of Ae. aegypti from La Guajira, Colombia. The frequency (diagnostic dose, DD) and intensity (2×, 5×, and 10× DD) of resistance to permethrin, deltamethrin, and lambda-cyhalothrin were determined in 15 populations of Ae. aegypti from La Guajira, Colombia, using the bottle bioassay. The kdr mutations V1016I, F1534C, and V410L, were identified, and their allele and genotype frequencies were calculated. Finally, the mortality values for the analyzed pyrethroids were interpolated following the IDW method for predicting pyrethroid resistance. The populations of Ae. aegypti showed a high frequency of resistance to permethrin with a low to moderate intensity, which was associated with the triple-resistant haplotype LL410/II1016/CC1534. They remain susceptible to deltamethrin and, in some populations, expressed the risk of developing resistance to lambda-cyhalothrin. Full article

(This article belongs to the Special Issue Insecticide Resistance: Challenge to Pest Management and Basic Research)

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Graphical abstract

Open AccessArticle

Analysis of the Feeding Behavior and Life Table of Nilaparvata lugens and Sogatella furcifera (Hemiptera: Delphacidae) under Sublethal Concentrations of Imidacloprid and Sulfoxaflor

and

Insects 2022, 13(12), 1130; https://doi.org/10.3390/insects13121130 - 07 Dec 2022

Cited by 1 | Viewed by 516

Abstract

The brown planthopper (BPH) Nilaparvata lugens and white-backed planthopper (WBPH) Sogatella furcifera are serious rice insect pests that cannot overwinter in Korea and migrate from southeast Asian countries and China. In this study, we investigated the sublethal effects of imidacloprid and sulfoxaflor on the biological parameters and feeding behavior of planthoppers. These sublethal concentrations significantly decreased the net reproduction rate (R₀), the intrinsic rate of increase (r_m), and the mean generation time (T). For BPHs, the total durations of nonpenetration (NP) waveform by imidacloprid (LC₁₀ = 164.74 and LC₃₀ = 176.48 min) and sulfoxaflor (LC₁₀ = 235.57 and LC₃₀ = 226.93 min) were significantly different from those in the control group (52.73 min). In addition, on WBPHs, the total durations of NP waveform by imidacloprid (LC₁₀ = 203.69 and LC₃₀ = 169.9 min) and sulfoxaflor (LC₁₀ = 134.02 and LC₃₀ = 252.14 min) were significantly different from those in the control group (45.18 min). Moreover, the LC₁₀ and LC₃₀ of these insecticides significantly decreased the phloem feeding time. In conclusion, imidacloprid had a better effect on the inhibition of feeding of the WBPH, and sulfoxaflor showed a better effect on the inhibition of feeding of the BPH. Therefore, it is suggested that treatment with sublethal concentrations of the above insecticides will reduce the feeding of BPHs and WBPHs on rice phloem. Full article

(This article belongs to the Special Issue Insecticide Resistance: Challenge to Pest Management and Basic Research)

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Open AccessFeature PaperArticle

Insecticide Susceptibility Status of Anopheles and Aedes Mosquitoes in Malaria and Dengue Endemic Areas, Thai–Myanmar Border

Kanchon Pusawang

Jetsumon Sattabongkot

Somsakul Pop Wongpalee

Liwang Cui

Atiporn Saeung

and

Patchara Sriwichai

Insects 2022, 13(11), 1035; https://doi.org/10.3390/insects13111035 - 09 Nov 2022

Viewed by 1011

Abstract

The occurrence and spread of insecticide resistance has had a negative effect on the efficacy of insecticide–based tools and is distributed worldwide, including the Greater Mekong Subregion (GMS). This study aims to determine the insecticide susceptibility of malaria and dengue vectors in malaria and dengue hotspots on the Thai–Myanmar border. Mosquito larvae and pupae were obtained from water sources from December 2019 to April 2020 in Tha Song Yang District, Tak province, western Thailand. WHO bioassay susceptibility tests were conducted with three classes of insecticides to evaluate the knockdown and mortality rates of Anopheles and Aedes aegypti female adults. V1016G and F1534C kdr mutations in the voltage-gated sodium channel of Ae. aegypti were identified using a multiplex PCR. A total of 5764 female mosquitoes were bioassayed in this study, including Anopheles spp. (92.63%) and F1 Ae. aegypti (7.37%). After 24 h of observation, An. minimus s.l. (n = 3885) and An. maculatus s.l. (n = 1138) in Suan Oi (SO) and Tala Oka (TO) were susceptible to pyrethroids, organophosphates and carbamates (except bendiocarb) with 98–100% mortality (MR). Resistance to bendiocarb was detected with a mortality rate of 88.80%, 88.77%, and 89.92% for An. minimus s.l. (n = 125, 125) and An. maculatus s.l. (n = 66), respectively. The first generation of Ae. aegypti adult females were suspected of resistance to deltamethrin (n = 225, MR = 96.89%) and confirmed resistance to permethrin (n = 200, MR = 20.00%). V1016G and F1534C mutations were detected in three genotypes, heterozygote and homozygote forms. The correlation between the kdr alleles and deltamethrin resistance was significant. In conclusion, bendiocarb resistance was found in primary malaria vectors, An. minimus s.l. and An. maculatus s.l. F1 Ae. aegypti population was pyrethroids-resistant, associated with kdr alleles. Therefore, molecular analysis should be conducted to gain insights into the mechanism of insecticide resistance. Routine malaria vector control programmes, such as fogging implementation in hotspot villages to induce Aedes resistance available in peri–domestic sites, are questionable. Full article

(This article belongs to the Special Issue Insecticide Resistance: Challenge to Pest Management and Basic Research)

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