Chemical Ecology in Host–Parasitoid Interactions: Signals, Strategies, and Survival

A special issue of Insects (ISSN 2075-4450).

Deadline for manuscript submissions: 30 September 2026 | Viewed by 1405

Special Issue Editor


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Guest Editor
Institute of Cotton Research, Chinese Academy of Agricultural Sciences, Anyang 455000, China
Interests: pest control; natural enemy; parasitoids
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Special Issue Information

Dear Colleagues,

Host–parasitoid interactions represent one of the most intricate and evolutionarily refined relationships in ecological systems, driven largely by chemical communication. This Special Issue explores the role of volatile organic compounds (VOCs), pheromones, and other chemical cues mediating these interactions. Contributions will highlight how parasitoids exploit host-derived chemical signals for localization and oviposition, as well as how hosts evolve counter-strategies, such as detoxification or behavioral avoidance. We welcome studies on molecular mechanisms, field-based ecological observations, and applied research leveraging these interactions for pest management. By synthesizing recent advances in chemical ecology, this Special Issue aims to uncover universal principles and context-dependent variations in these dynamic systems.

Dr. Xueke Gao
Guest Editor

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Keywords

  • chemical ecology
  • host–parasitoid interactions
  • volatile organic compounds (VOCs)
  • pest management
  • co-evolution

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Published Papers (1 paper)

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Research

14 pages, 1071 KB  
Article
Molecular Basis for Stage-Specific Host Preference in the Aphid Parasitoid Binodoxys communis
by Tingfang Zhong, Cen Bai, Jinming Li, Li Wang, Kaixin Zhang, Dongyang Li, Jichao Ji, Xiangzhen Zhu, Xueke Gao and Weihua Ma
Insects 2025, 16(11), 1127; https://doi.org/10.3390/insects16111127 - 4 Nov 2025
Cited by 1 | Viewed by 1132
Abstract
The cotton aphid Aphis gossypii is a globally significant agricultural pest that threatens crop production through its prolific reproduction. While the parasitoid wasp Binodoxys communis offers promising potential for biological control, the molecular mechanisms underlying its reproductive manipulation of aphid hosts remain poorly [...] Read more.
The cotton aphid Aphis gossypii is a globally significant agricultural pest that threatens crop production through its prolific reproduction. While the parasitoid wasp Binodoxys communis offers promising potential for biological control, the molecular mechanisms underlying its reproductive manipulation of aphid hosts remain poorly understood. Here, we investigated the stage-specific parasitism strategies of B. communis on A. gossypii using integrated biological observations and transcriptomic analysis. Parasitism significantly prolonged aphid development and suppressed reproduction across all host stages, with severity inversely correlated with host age at parasitism. Transcriptomic analysis of ovaries of parasitized aphids revealed 1168 differentially expressed genes, with temporal progression from minimal changes in nymphs (7 DEGs at day 1) to extensive disruption in adults (549 DEGs at day 3). Notably, juvenile hormone acid methyltransferase (JHAMT), the rate-limiting enzyme in juvenile hormone biosynthesis, emerged as a master regulator that is differentially targeted across host stages. In 3rd instar nymphs, single-gene suppression of JHAMT (−3.23-fold change) achieved effective reproductive control, whereas adult parasitism required progressive manipulation of multiple genes including JHAMT, FOHSDR, ALDH, and JHEH. The vitellogenin-vitellogenin receptor system only showed coordinated downregulation in adults, whereas nymphs exhibited preemptive receptor suppression before vitellogenesis onset. These findings demonstrate that B. communis has evolved to exploit a developmental window where host manipulation is most efficient—3rd instar nymphs, which possess sufficient resources for parasitoid development and lack the complex compensatory mechanisms found in adults. This “low-cost, high-reward” strategy based on precision targeting of master regulators in nymphs compared to multi-gene assault in adults, revealing the evolutionary optimization of parasitoid manipulation strategies. Our results provide molecular insights into parasitoid-host coevolution and identified key regulatory targets for developing innovative biological control strategies against this important agricultural pest. Full article
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