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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cutting-Edge Methods for Exploiting Bioactive Compounds in Biomasses: From the Plant Matrix to Molecular Function
edited by Chiara Magni
submission deadline 20 Oct 2025 | 2 articles | Viewed by 2219 | Submission Open
Keywords: plant matrix; agri-food biomasses; biochemistry; bioactive compounds
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Macrophages and Inflammation
edited by
submission deadline 20 Oct 2025 | 1 articles | Viewed by 2130 | Submission Open
Keywords: innate immunity; transcriptional programs; epigenetics; immunometabolism; receptors; scavenging; cytokines; ROS
(This special issue belongs to the Section Molecular Immunology)
Molecular Studies of Mutations Related to Neurodegenerative Diseases
edited by
submission deadline 20 Oct 2025 | 2 articles | Viewed by 2118 | Submission Open
Keywords: SNPs; mutations; structural effects; transcriptional regulation; splicing; translational regulation; post-transcriptional regulation; post-translational regulation; haploinsufficiency; nonsense mediated decay; in silico analysis; experimental analysis; missense; nonsense; frameshift; epigenetics; non-coding; coding; function alteration; stability alteration
(This special issue belongs to the Section Molecular Neurobiology)
Exploring the Molecular Basis of Cellular Responses to Microgravity-Induced Oxidative Stress submission deadline 20 Oct 2025 | 2 articles | Viewed by 2107 | Submission Open
Keywords: microgravity; reactive oxygen species (ROS); oxidative damage; cellular antioxidant systems; cell metabolism; cell responses; molecular pathways; simulated microgravity; protective countermeasures
(This special issue belongs to the Section Molecular Biology)
Roles of Mast Cells in Immune-Induced Diseases
edited by Paul L.A. Van Daele and Willem A. Dik
submission deadline 20 Oct 2025 | 1 articles | Viewed by 2095 | Submission Open
Keywords: mast cell; fibrosis; inflammation; autoinflammation; autoimmunity; transplantation; gastrointestinal; pulmonary; cytokines; MRGPRX2; rejection
(This special issue belongs to the Section Molecular Immunology)
Cyclodextrins for Drug/iRNA Co-Delivery
edited by and
submission deadline 20 Oct 2025 | 1 articles | Viewed by 2057 | Submission Open
Keywords: advanced therapies; antibody-based therapies; active and passive tumor targeting; cancer; conventional chemotherapy; immune system; immunotherapy; immunotoxicity; nanomedicine; nanoparticles; nanotoxicity; tumor immune microenvironment (TIME); tumor microenvironment (TME); cyclodextrins
(This special issue belongs to the Section Macromolecules)
Mitochondrial Metabolism Alterations in Health and Disease: 2nd Edition submission deadline 20 Oct 2025 | 1 articles | Viewed by 2027 | Submission Open
Keywords: mitochondrial Metabolism; mitochondrial disorders; cellular processes; dysregulation organisms’ physiology
(This special issue belongs to the Section Biochemistry)
Newer Pharmacological Treatment Concepts for Patients with Acute Coronary Syndrome submission deadline 20 Oct 2025 | 2 articles | Viewed by 2002 | Submission Open
Keywords: acute coronary syndrome (ACS); molecular studies; antiplatelet; anticoagulant drugs; lipid-lowering therapies
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Research on Osteogenesis submission deadline 20 Oct 2025 | 1 articles | Viewed by 1999 | Submission Open
Keywords: osteogenesis; bone reconstruction; bone regeneration; bone disease
(This special issue belongs to the Section Molecular Biology)
Signaling in Respiratory Diseases
edited by Tonio Pera
submission deadline 20 Oct 2025 | 1 articles | Viewed by 1985 | Submission Open
Keywords: asthma; COPD; cystic fibrosis; GPCR; pharmacology; inflammation; airway remodeling
(This special issue belongs to the Section Molecular Biology)
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