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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Mechanisms and Treatment of Migraine
edited by Noboru Imai
submission deadline 20 Oct 2025 | 1 articles | Viewed by 2767 | Submission Open
Keywords: migraine; nitric oxide synthase (NOS); neuropeptides; calcitonin gene-related peptide (CGRP); pituitary adenylate cyclase activating polypeptide (PACAP); molecular pathways; therapeutic targets; neurovascular condition
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Mechanistic Insights into Cancer Immunotherapy and Immune-Related Adverse Events
edited by Noha Abdel-Wahab, and Kristen E. Pauken
submission deadline 20 Oct 2025 | 1 articles | Viewed by 2758 | Submission Open
Keywords: cancer immunotherapy; immune-related adverse events; biomarker; immune checkpoint inhibitor; cancer progression
(This special issue belongs to the Section Molecular Oncology)
Molecular Pathways and Therapeutic Strategies for Fibrotic Conditions
edited by
submission deadline 20 Oct 2025 | 2 articles | Viewed by 2702 | Submission Open
Keywords: fibrosis; fibrotic disorders; autoimmune diseases; cancer; adipose tissue fibrosis; repurposed drugs; gene therapies; cytokine-mediated pathways; anti-fibrotic therapies; systemic diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Insights into Plant and Insect Interactions (Second Edition)
edited by and Xiaoling Sun
submission deadline 20 Oct 2025 | 3 articles | Viewed by 2692 | Submission Open
Keywords: plant defense responses; elicitors; effectors; defense-related signaling; insect– plant interactions; tritrophic interactions; detoxification; defensive compounds; defensive genes
(This special issue belongs to the Section Molecular Plant Sciences)
Antimicrobial Resistance, Molecular Mechanisms and Fight Strategies: 4th Edition submission deadline 20 Oct 2025 | 2 articles | Viewed by 2605 | Submission Open
Keywords: antimicrobial resistance; mechanisms of antimicrobial resistance; rapid antimicrobial-sensitive assays; drug discovery; antibiotics; vaccine; monoclonal antibodies; infectious diseases
(This special issue belongs to the Section Molecular Microbiology)
Opportunities and Challenges in the Use of Live Biotherapeutics to Fight Infections in the Era of Multi-Drug-Resistance
edited by
submission deadline 20 Oct 2025 | 1 articles | Viewed by 2582 | Submission Open
Keywords: probiotics; postbiotics; bioengineered probiotics; engineered bacterium; next-generation probiotics; phage; phage therapy; multi-drug-resistant organisms; microbiota replacement; live biotherapeutic product
(This special issue belongs to the Section Molecular Immunology)
Molecular Research on Diabetes—2nd Edition submission deadline 20 Oct 2025 | 3 articles | Viewed by 2550 | Submission Open
Keywords: diabetes; insulin; glucose metabolism; oxidative stress
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
The Role of Mesenchymal Stem Cells in Organ Repair and Tissue Regeneration
edited by
submission deadline 20 Oct 2025 | 4 articles | Viewed by 2532 | Submission Open
Keywords: stem cells; differentiation; cell therapy; tissue regeneration; cell mechanisms; regenerative medicine; immunomodulation
(This special issue belongs to the Section Molecular Biology)
Depression: From Molecular Basis to Therapy—2nd Edition
edited by
submission deadline 20 Oct 2025 | 3 articles | Viewed by 2457 | Submission Open
Keywords: depression; neurobiology; molecular basis; neurotransmitters; genetic factors; psychopharmacology; psychotherapy; genetic markers
(This special issue belongs to the Section Molecular Neurobiology)
The Role of Phytohormones in Plant Biotic/Abiotic Stress Tolerance
edited by
submission deadline 20 Oct 2025 | 1 articles | Viewed by 2405 | Submission Open
Keywords: biotic/abiotic stress; phytohormone; resistance to stress
(This special issue belongs to the Section Molecular Plant Sciences)
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