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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Mitochondrial and Energy Metabolic Function in Heart and Skeletal Muscle
edited by Yoshitake Cho
submission deadline 20 Oct 2025 | 1 articles | Viewed by 6269 | Submission Open
Keywords: heart; skeletal muscle; metabolism; glucose; mitochondria; metabolic disorder
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
New Advances in Epigenetics and Epigenomics
edited by Vicki Maltby
submission deadline 20 Oct 2025 | 4 articles | Viewed by 5975 | Submission Open
Keywords: epigenetics; epigenomics; multi-omics; epitranscriptomics; single cell
(This special issue belongs to the Section Molecular Genetics and Genomics)
Exosomes—3rd Edition
edited by
submission deadline 20 Oct 2025 | 4 articles | Viewed by 5975 | Submission Open
Keywords: extracellular vesicles (EVs); exosomes; cancer; sleep cardiovascular diseases; lung disease and upper airways; obesity; sleep and end-organ morbidity
(This special issue belongs to the Section Molecular Biology)
Extracellular Vesicles: From Molecular Mechanisms to Therapeutic Applications
edited by Jung-Hyun Lee
submission deadline 20 Oct 2025 | 6 articles | Viewed by 5973 | Submission Open
Keywords: extracellular vesicles; intercellular communications; biomarkers; drug delivery systems
(This special issue belongs to the Section Biochemistry)
Advanced Research in Plant–Fungus Interactions: Second Edition
edited by
submission deadline 20 Oct 2025 | 3 articles | Viewed by 5775 | Submission Open
Keywords: plant– fungus interactions; symbiotic association; endophytes; plant conservation; mycorrhizal symbioses
(This special issue belongs to the Section Molecular Plant Sciences)
Novel Extracellular Vesicle-Based Therapy for Central Nervous System Diseases
edited by Andrea Cabrera-Pastor
submission deadline 20 Oct 2025 | 2 articles | Viewed by 5766 | Submission Open
Keywords: extracellular vesicles (EVs); exosomes; therapy; CNS disorders; neuroinflammation; signal transduction; mechanism; interorgan crosstalk; biomarker; EVs from MSCs; drug delivery
(This special issue belongs to the Section Molecular Neurobiology)
Brain Plasticity in Health and Disease
edited by
submission deadline 20 Oct 2025 | 2 articles | Viewed by 5308 | Submission Open
Keywords: brain plasticity; brain structure and function; cerebral cortex; cerebellum; neurological disorders; neuropsychiatric disorders; neurophysiology; computational modeling; brain imaging; Neuroplasticity
(This special issue belongs to the Section Molecular Neurobiology)
Metabolic Dysfunction-Associated Steatotic Liver Disease: From Basic Science to Therapy
edited by
submission deadline 20 Oct 2025 | 4 articles | Viewed by 5229 | Submission Open
Keywords: MASLD; liver steatosis; steatohepatitis; liver cirrhosis; hepatocellular carcinoma; in vivo; in vitro; therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Insights into Liver Biology and Disease Pathogenesis: Shedding Light on Novel Diagnostic and Therapeutic Approaches submission deadline 20 Oct 2025 | 3 articles | Viewed by 5096 | Submission Open
Keywords: liver molecular biology; novel biomarkers; liver regeneration; liver repair; liver carcinogenesis; brain– gut– liver axis; novel therapeutic targets; molecular diagnostic tools; host– pathogen interactions; novel in vitro and in vivo models of liver diseases  
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research and Treatment in Multiple Sclerosis
edited by Nada Starčević Čizmarević and
submission deadline 20 Oct 2025 | 3 articles | Viewed by 4968 | Submission Open
Keywords: multiple sclerosis; neuroinflammation; neurodegeneration; genetics; molecular research; biomarkers; neuroimaging; therapy
(This special issue belongs to the Section Molecular Biology)
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