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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Iron Metabolism in Cancer: Mechanisms and Therapeutic Targeting
edited by Michael Petronek
submission deadline 28 Feb 2027 | Viewed by 42 | Submission Open
Keywords: iron metabolism; redox biology; ferroptosis; tumor progression; cancer therapy; iron–sulfur clusters; heme proteins; ferritinophagy
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Recent Advances in Brain Tumours submission deadline 28 Feb 2027 | Viewed by 41 | Submission Open
Keywords: IGF; glioblastoma; nephroblastoma; cancer genetics; antisense therapy
(This special issue belongs to the Section Molecular Oncology)
Pyroptosis, Ferroptosis and Necroptosis in Cardiovascular Diseases
edited by
submission deadline 28 Feb 2027 | Viewed by 38 | Submission Open
Keywords: pyroptosis; ferroptosis; necroptosis; inflammation; NLRP3 inflammasome; pro-inflammatory cytokines; lipid peroxidation; oxidative stress; receptor-interacting protein kinases (RIPKs); mixed lineage kinase domain-like protein (MLKL)
(This special issue belongs to the Section Molecular Biology)
Pathogenesis of Endometriosis, Disease Stratification, Diagnosis and Therapy
edited by Katharina Proestling and
submission deadline 28 Feb 2027 | Viewed by 38 | Submission Open
Keywords: endometriosis; biomarkers; inflammation; fibrosis; oxidative stress; epigenetics; genetics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Mechanisms of Extracellular Electron Transfer Across Phylogenetically Diverse Microorganisms
edited by Fengjie Zhao and Sukrampal Yadav
submission deadline 28 Feb 2027 | Viewed by 37 | Submission Open
Keywords: electroactive microorganisms; extracellular electron transfer; molecular mechanisms; microbial electrochemistry; phylogenetic diversity
(This special issue belongs to the Section Molecular Microbiology)
Advances in Molecular and Cellular Mechanisms of Autoimmune Diseases
edited by Stelvio Tonello and
submission deadline 28 Feb 2027 | Viewed by 36 | Submission Open
Keywords: autoimmunity; NETosis; biomarkers; pathology; autoimmune disease; pharmacological response; immunological modulation
(This special issue belongs to the Section Molecular Immunology)
Viral Infections and Immune Responses—2nd Edition submission deadline 28 Feb 2027 | Viewed by 36 | Submission Open
Keywords: virus; infections; immune response; T-cells; B-cells; antibodies; neutralising activity
(This special issue belongs to the Section Molecular Immunology)
Metabolic Programming: Control of Gene Expression in Health and Disease
edited by
submission deadline 28 Feb 2027 | Viewed by 35 | Submission Open
Keywords: metabolic programming; gene regulation; immunometabolism; oncometabolism; acetyl-CoA; epigenetics; transcription; NAD; one-carbon metabolism; metabolic biosensors
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Inflammatory, Metabolic, and Redox Biomarkers in Oncology submission deadline 28 Feb 2027 | Viewed by 34 | Submission Open
Keywords: oncology; biomarkers; inflammation; cancer metabolism; oxidative stress; redox biology; tumor microenvironment; treatment response; therapeutic resistance; precision oncology
(This special issue belongs to the Section Molecular Oncology)
RNA Regulation and Satellite Cell-Opathies: Molecular Pathogenesis and Therapeutic Frontiers in Neuromuscular Diseases submission deadline 28 Feb 2027 | Viewed by 34 | Submission Open
Keywords: satellite cells; neuromuscular disorders; alternative splicing; satellite cell-opathies; RNA-binding proteins; RNA therapeutics; molecular pathogenesis; myogenesis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
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