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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Mechanisms of Hypertension
edited by Pedro A. José
submission deadline 30 Sep 2025 | Viewed by 11 | Submission Open
Keywords: salt sensitivity; inverse salt sensitivity; epigenetics; genetics; organ-to-organ communication
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Metal Toxicity and Particle Toxicity
edited by Alicja Piotrowska-Niczyporuk
submission deadline 30 Sep 2025 | Viewed by 11 | Submission Open
Keywords: metals; particles; toxicity; microplastic; environment pollution; animals; plants; algae
(This special issue belongs to the Section Molecular Toxicology)
New Perspectives in Protein Structure
edited by
submission deadline 30 Sep 2025 | Viewed by 10 | Submission Open
Keywords: stability of protein complexes structural; background of protein function; allosteric regulation of proteins; fuzzy complexes; intrinsically disordered proteins; liquid-liquid phase separation; mutual synergistic folding; protein folding; protein structure; protein-protein interactions; transmembrane proteins
(This special issue belongs to the Section Molecular Biophysics)
Molecular and Cellular Pathways Involved in Age-Related Musculoskeletal Disorders
edited by and Neha Dole
submission deadline 1 Oct 2025 | Viewed by 76 | Submission Open
Keywords: musculoskeletal disorders; cellular senescence; aging; genetic mutations; oxidative stress; mitochondrial dysfunction; bone homeostasis
(This special issue belongs to the Section Molecular Biology)
Surfactants: Design, Synthesis and Application
edited by
submission deadline 9 Oct 2025 | Viewed by 85 | Submission Open
Keywords: surfactants; adsorption phenomena; critical micellar concentration (CMC); hydrophilic– lipophilic balance (HLB); critical packing parameter (CPP); emulsion formulations; vesicular and non-vesicular origin nanocarriers; drug delivery; theranostics
(This special issue belongs to the Section Materials Science)
A Metabolomics Approach to Tackling Toxicological and Pharmacological Issues: 2nd Edition submission deadline 10 Oct 2025 | 2 articles | Viewed by 4055 | Submission Open
Keywords: metabolomics; metabolites; drugs; contaminants; xenobiotics; toxicity; pharmacology; toxicology
(This special issue belongs to the Section Molecular Toxicology)
Recent Advances in Graphene-Based Nanocomposites and Perspectives on Their Design
edited by Aleksey E. Kuznetsov
submission deadline 10 Oct 2025 | Viewed by 38 | Submission Open
Keywords: graphene; graphene oxide; nanocomposite; synthesis; computational study; characterization; application; design
(This special issue belongs to the Section Molecular Nanoscience)
Chlamydia trachomatis Pathogenicity and Disease (Third Edition) submission deadline 10 Oct 2025 | Viewed by 30 | Submission Open
Keywords: Chlamydia trachomatis; virulence factors; host susceptibility or resistance; innate and adaptive immune responses; genetic studies; cervico-vaginal microbiota; clinical outcomes with molecular study
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
MDSCs in Health and Disease submission deadline 10 Oct 2025 | Viewed by 19 | Submission Open
Keywords: MDSCs; inflammation; immune regulation; cancer; autoimmune diseases; pregnancy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Genetics of Human Disease: Emphasis on X-Linked Diseases and Clinical Practice
edited by Antonella La Russa
submission deadline 15 Oct 2025 | Viewed by 280 | Submission Open
Keywords: rare diseases; X-linked disease; X chromosome inactivation (XCI); mosaicism; epigenome; undiagnosed rare diseases; phenotype– genotype correlations; biomarkers; personalized medicine; precision medicine
(This special issue belongs to the Section Molecular Genetics and Genomics)
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