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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Antimicrobial Agents and the Quest for Resistance Breakthroughs
edited by
submission deadline 30 Sep 2025 | Viewed by 30 | Submission Open
Keywords: drug resistance; antimicrobial resistance (AMR); drug-resistant bacteria; drug-resistant viruses; drug-resistant fungi; drug-resistant parasite; drug resistance biomolecular studies; mechanism of resistance; novel antimicrobial agents; treatment of infectious diseases
(This special issue belongs to the Section Molecular Pharmacology)
3D Cell and Tissue Culture Systems: Benefits to Research and Disease Diagnostics
edited by
submission deadline 30 Sep 2025 | Viewed by 30 | Submission Open
Keywords: 3D physiological relevance vs. 2D biology; 3D research; and diagnostic systems; evolving 3D “ omics” applications; research and clinical medicine; drug applications; toxicity evaluations
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Microbial Interactions with Insect Hosts: Mechanisms, Evolution and Ecological Implications
edited by Jin-Hua Xiao
submission deadline 30 Sep 2025 | Viewed by 30 | Submission Open
Keywords: insect-microbe symbiosis; host-microbe coevolution; microbial-mediated behavior; insect adaptive evolution; cross-domain evolution
(This special issue belongs to the Section Molecular Microbiology)
Marine Fungi: From Molecular Biology to Biotechnology Application
edited by
submission deadline 30 Sep 2025 | Viewed by 29 | Submission Open
Keywords: marine fungi; marine yeasts; marine filamentous fungi; biosynthesis; metabolic engineering; regulatory mechanism; functional biomolecules; exopolysaccharides; glycolipids; organic acids; biofuel; enzymes; cell factories; gene editing tools; fermentation optimization
(This special issue belongs to the Section Molecular Microbiology)
Advances in Molecular Research on Candida Resistance
edited by
submission deadline 30 Sep 2025 | Viewed by 29 | Submission Open
Keywords: Candida resistance; antifungal resistance; biofilm; drug repurposing; novel therapies; molecular mechanisms; antifungal agents; Candida albicans; Candida auris; host– pathogen interactions
(This special issue belongs to the Section Molecular Microbiology)
Unraveling the Molecular Crosstalk Between Ferroptosis and Tumorigenesis
edited by
submission deadline 30 Sep 2025 | Viewed by 29 | Submission Open
Keywords: tumorigenesis; ferroptosis; cancer biology; tumor development
(This special issue belongs to the Section Molecular Oncology)
Targeting MAPK in Human Diseases
edited by
submission deadline 30 Sep 2025 | Viewed by 29 | Submission Open
Keywords: ERK; DUSP; cancer; inflammation; neurodegenerative diseases; autoimmune diseases; targeted therapy; cell signaling
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Hydrogels and Nanogels: Revolutionizing Drug Delivery and Disease Detection
edited by Enrico Gallo
submission deadline 30 Sep 2025 | Viewed by 28 | Submission Open
Keywords: hydrogel and nanogel networks; supramolecular systems; hydrogel synthesis and analysis; nanogel preparation and characterization; nanostructured fibers; multiphase gels; biomedicine applications; supramolecular probes for imaging; hydrogels and nanogels as drug release systems; coatings and surface treatments; polymeric systems; peptide-based supramolecular systems
(This special issue belongs to the Section Materials Science)
Biochemical Advancements in Filler Technology and Their Impact on Tissue Engineering
edited by Samuel J. Lin
submission deadline 30 Sep 2025 | Viewed by 28 | Submission Open
Keywords: biochemical filler technology; tissue regeneration; bioactive materials; injectable scaffolds; molecular signaling in tissue engineering; biomaterials for soft tissue repair; filler– cell interactions; regenerative esthetics
(This special issue belongs to the Section Biochemistry)
Genetics and Omics in Autoimmune Diseases submission deadline 30 Sep 2025 | Viewed by 28 | Submission Open
Keywords: autoimmune diseases; genetics; genomics; omics; single-nucleotide variants; copy number variants; variation; susceptibility; mRNAs; microRNAs; long non-coding RNAs; masive sequencing
(This special issue belongs to the Section Molecular Genetics and Genomics)
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